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In vitro activities of 15 oral beta-lactams against Klebsiella pneumoniae harboring new extended-spectrum beta-lactamases.

作者信息

Kitzis M D, Liassine N, Ferré B, Gutmann L, Acar J F, Goldstein F

机构信息

Laboratoire de Microbiologie Médicale, Hôpital Saint-Joseph, Paris, France.

出版信息

Antimicrob Agents Chemother. 1990 Sep;34(9):1783-6. doi: 10.1128/AAC.34.9.1783.

Abstract

The activities of 15 oral beta-lactams against Klebsiella pneumoniae harboring new extended-spectrum beta-lactamases were studied. All compounds were affected by these enzymes, especially by the SHV derivatives. Except for ceftibuten, the compounds with the greatest intrinsic activity were more affected by the presence of these enzymes than were older compounds with moderate intrinsic activity.

摘要

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