Jung J S, Chung C H, Lee S H, Cho S H, Lee J H, Ryu J G, Song H, Lee J W, Choo S J
Department of Thoracic and Cardiovascular Surgery, Anam Hospital, Korea University Medical Center, Seoul, Korea.
J Cardiovasc Surg (Torino). 2012 Aug;53(4):537-44.
The present study was aimed to compare the hemodynamic flow characteristics of LIMA radial artery composite sequential bypass grafting and with single LIMA and saphenous vein sequential bypass grafting performed by off-pump coronary artery bypass grafting (OPCAB).
Between March 2007 and February 2008, 121 OPCAB patients were prospectively divided into two groups; Group I (N.=70, left internal thoracic artery [LITA]-left anterior descending [LAD] and Ao-SV sequential grafting), and Group II (N.=51, LITA-RA sequential grafting). The mean flow, pulsatility index (PI) and back flow (BF) were measured using the Transit-time flow meter (TTFM). In Group II, the proximal (p-LITA) and distal LITA (d-LITA) flow in relation to the RA side branch anastomosis were measured separately.
The mean flow and PI of the proximal SV sequential graft and that of the RA graft were 64.4 ± 37.3 mL/min and 2.6 ± 1.6 versus 27.3 ± 18.6 mL/min and 4.1 ± 4.4, respectively (P<0.05). In Group I, the mean LITA flow, PI, and BF were 26.9 ± 16.4 mL/min, 2.6 ± 1.5, and 3.1 ± 6.1% whereas in Group II those of the p-LITA were 37.3 ± 21.6 mL/min, 2.3 ± 1.0, and 2.0 ± 3.5% and the d-LITA were 18.8 ± 12.2 mL/min, 3.9 ± 3.3 and 7.4 ± 11.8% (P<0.01).
The results of the present data suggest the hemodynamic flow characteristics of composite bypass grafting to be inferior to the single LIMA and separate aorta-saphenous vein bypass grafting strategy. However, a longer follow up is warranted to assess the implications of these findings on graft durability.
本研究旨在比较非体外循环冠状动脉旁路移植术(OPCAB)下行左乳内动脉-桡动脉复合序贯旁路移植术与单纯左乳内动脉和大隐静脉序贯旁路移植术的血流动力学特征。
2007年3月至2008年2月,121例行OPCAB的患者被前瞻性地分为两组;第一组(n = 70,左乳内动脉[LITA]-左前降支[LAD]及主动脉-大隐静脉序贯移植)和第二组(n = 51,LITA-桡动脉序贯移植)。使用渡越时间血流仪(TTFM)测量平均血流、搏动指数(PI)和反流(BF)。在第二组中,分别测量与桡动脉侧支吻合相关的近端(p-LITA)和远端LITA(d-LITA)血流。
近端大隐静脉序贯移植和桡动脉移植的平均血流和PI分别为64.4±37.3 mL/min和2.6±1.6,而桡动脉移植的分别为27.3±18.6 mL/min和4.1±4.4(P<0.05)。在第一组中,LITA平均血流、PI和BF分别为26.9±16.4 mL/min、2.6±1.5和3.1±6.1%,而在第二组中,p-LITA的分别为37.3±21.6 mL/min、2.3±1.0和2.0±3.5%,d-LITA的分别为18.8±12.2 mL/min、3.9±3.3和7.4±11.8%(P<0.01)。
目前的数据结果表明复合旁路移植术的血流动力学特征不如单纯左乳内动脉和单独的主动脉-大隐静脉旁路移植术策略。然而,需要更长时间的随访来评估这些发现对移植物耐久性的影响。