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谁在使用氨基葡萄糖以及为什么使用?一项对 266848 名 45 岁及以上澳大利亚人的研究。

Who uses glucosamine and why? A study of 266,848 Australians aged 45 years and older.

机构信息

School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.

出版信息

PLoS One. 2012;7(7):e41540. doi: 10.1371/journal.pone.0041540. Epub 2012 Jul 30.

Abstract

OBJECTIVES

There has been a dramatic increase in the use of complementary medicines over recent decades. Glucosamine is one of the most commonly used complementary medicines in Western societies. An understanding of glucosamine consumption is of significance for public health and future health promotion. This paper, drawing upon the largest dataset to date with regards to glucosamine use (n = 266,844), examines the use and users of glucosamine amongst a sample of older Australians.

DESIGN

Analysis of the self-reported data on use of glucosamine, demographics and health status as extracted from the dataset of the 45 and Up Study, which is the largest study of healthy ageing ever undertaken in the Southern Hemisphere involving over 265,000 participants aged 45 and over.

RESULTS

Analysis reveals that 58,630 (22.0%) participants reported using glucosamine in the 4 weeks prior to the survey. Use was higher for those who were female, non-smokers, residing in inner/outer regional areas, with higher income and private health insurance. Of all the health conditions examined only osteoarthritis was positively associated with use of glucosamine, while cancer, heart attack or angina and other heart disease were all negatively associated with glucosamine use.

CONCLUSIONS

This study suggests that a considerable proportion of the Australia population aged 45 and over consume glucosamine. There is a need for health care practitioners to enquire with their patients about their use of glucosamine and for further attention to be directed to providing good quality information for patients and providers with regards to glucosamine products.

摘要

目的

近几十年来,人们对补充药物的使用急剧增加。氨基葡萄糖是西方社会最常用的补充药物之一。了解氨基葡萄糖的使用情况对公共卫生和未来的健康促进具有重要意义。本文利用迄今为止关于氨基葡萄糖使用情况(n=266844)的最大数据集,研究了老年澳大利亚人群中氨基葡萄糖的使用情况和使用者。

设计

分析从 45 岁及以上研究中提取的关于氨基葡萄糖使用、人口统计学和健康状况的自我报告数据,该研究是南半球迄今为止进行的最大的健康老龄化研究,涉及超过 265000 名 45 岁及以上的参与者。

结果

分析显示,266844 名参与者中有 58630 名(22.0%)在调查前 4 周内报告使用过氨基葡萄糖。女性、不吸烟者、居住在内部/外部区域、收入较高和拥有私人医疗保险的人使用氨基葡萄糖的比例较高。在所检查的所有健康状况中,只有骨关节炎与使用氨基葡萄糖呈正相关,而癌症、心脏病发作或心绞痛和其他心脏病则与使用氨基葡萄糖呈负相关。

结论

本研究表明,相当一部分 45 岁及以上的澳大利亚人服用氨基葡萄糖。医疗保健从业者有必要询问他们的患者是否使用氨基葡萄糖,并进一步关注为患者和提供者提供有关氨基葡萄糖产品的高质量信息。

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