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ACS chemical neuroscience molecule spotlight on BMS-708163.
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BMS-708,163 targets presenilin and lacks notch-sparing activity.
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Synthesis and structure-activity relationship of a novel series of heterocyclic sulfonamide gamma-secretase inhibitors.
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Synthesize heterogeneous biological knowledge via representation learning for Alzheimer's disease drug repurposing.
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Practical Method for Preparation of ()-2-Amino-5,5,5-trifluoropentanoic Acid via Dynamic Kinetic Resolution.
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Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor.
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ACS chemical neuroscience molecule spotlight on Begacestat (GSI-953).
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ACS chemical neuroscience molecule spotlight on semagacestat (LY450139).
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