不同剂量的铁扫把籽提取物对白化大鼠卵巢和子宫的影响。
Effect of graded doses of Caesalpinia bonducella seed extract on ovary and uterus in albino rats.
作者信息
Salunke Kanchan R, Ahmed R Nazeer, Marigoudar Shambanagouda R
机构信息
Karnatak University, Karnataka, India.
出版信息
J Basic Clin Physiol Pharmacol. 2011 Jun 17;22(1-2):49-53. doi: 10.1515/jbcpp.2011.006.
Histological changes observed under light microscope illustrate follicular degeneration in ovary, vacuolation and mild disorganization of uterus on treatment with graded doses of alcohol seed extract of Caesalpinia bonducella. There was a significant decrease (p≤0.05) in duration of estrous cycle and mean ovarian weight. However, there were no uniform variations in mean uterine weight, serum estradiol and progesterone level. The results suggest that alcohol seed extract of C. bonducella has antiestrogenic property, possibly acting via inhibition of estrogen secretion.
在光学显微镜下观察到的组织学变化表明，用不同剂量的铁藤酒精种子提取物处理后，卵巢出现卵泡退化，子宫出现空泡化和轻度结构紊乱。发情周期持续时间和平均卵巢重量显著降低（p≤0.05）。然而，平均子宫重量、血清雌二醇和孕酮水平没有一致的变化。结果表明，铁藤酒精种子提取物具有抗雌激素特性，可能通过抑制雌激素分泌起作用。
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