Faculty of Life Sciences, Dr. H.S. Gour University, Sagar, Madhya Pradesh, India.
Pharm Biol. 2010 Feb;48(2):227-30. doi: 10.3109/13880200903085474.
This study evaluated the in vivo immunomodulatory activities of the aqueous extract of Caesalpinia bonducella Fleming (Caesalpiniaceae) seeds. C. bonducella is a plant widely used in the traditional medicinal systems of India. In the present investigation, the aqueous extract of C. bonducella seeds was tested for its effect on cell mediated and humoral components of the immune system in rats. Administration of C. bonducella seed extract produced an increase of 93.03 +/- 4 mean hemagglutinating antibody (HA) titer and a change of 0.56 +/- 0.058 mm in delayed type hypersensitivity (DTH) as compared to control at a dose of 400 mg/kg body weight. Thus, the results of this study indicate that C. bonducella extract could be a promising immunostimulatory agent.
本研究评估了刺桐（豆科）种子水提物的体内免疫调节活性。刺桐是一种在印度传统医学体系中广泛应用的植物。在本研究中，检测了刺桐种子水提物对大鼠细胞介导和体液免疫成分的影响。与对照组相比，在 400mg/kg 体重剂量下，刺桐种子提取物可使血凝抗体（HA）滴度增加 93.03±4 个均值，迟发型超敏反应（DTH）变化 0.56±0.058mm。因此，本研究结果表明，刺桐提取物可能是一种有前途的免疫刺激剂。
