Hayton Emma, Wakerley Benjamin, Bowler Ian Cjw, Bogdanovic Marko, Adcock Jane Elizabeth
Department of Microbiology, John Radcliffe Hospital, Oxford, UK.
Pract Neurol. 2012 Aug;12(4):234-7. doi: 10.1136/practneurol-2012-000234.
We present a 19-year-old woman with severe encephalitis and raised intracranial pressure requiring decompressive craniectomy. Her clinical features were consistent with encephalitis in the context of acute primary Epstein-Barr virus (EBV) infection (infectious mononucleosis). Serology, bone marrow aspirate and PCR of blood and cerebrospinal fluid confirmed the diagnosis. She was treated with corticosteroids and aciclovir. She was critically unwell for 3 weeks, requiring artificial ventilation but eventually made a good recovery. EBV encephalitis is uncommon, making the diagnosis and decisions about clinical management challenging.
我们报告了一名19岁女性，患有严重脑炎且颅内压升高，需要进行减压颅骨切除术。她的临床特征与急性原发性爱泼斯坦-巴尔病毒（EBV）感染（传染性单核细胞增多症）背景下的脑炎相符。血清学、骨髓穿刺以及血液和脑脊液的聚合酶链反应（PCR）确诊了该诊断。她接受了皮质类固醇和阿昔洛韦治疗。她病情严重达3周，需要人工通气，但最终恢复良好。EBV脑炎并不常见，这使得诊断和临床管理决策具有挑战性。
