Dagdemir Ayhan, Tasdemir Haydar Ali, Dilber Cengiz, Gok Faysal, Kubar Ayhan
Department of Pediatrics, Ondokuz Mayis University, Medical Faculty, Samsun, Turkey.
Pediatr Neurol. 2006 Nov;35(5):352-5. doi: 10.1016/j.pediatrneurol.2006.05.014.
Central nervous system involvement in Epstein-Barr virus infection usually presents as meningitis, encephalitis, or encephalomyelitis, mostly in the acute form of the disease. In chronic active infection, the clinical situation may also resemble acute infection as well findings of chronic inflammation such as calcification. This report presents an 8-year-old female with chronic active Epstein-Barr virus infection and encephalitis complicated by increased intracranial pressure who was managed with repeated lumbar punctures and medical treatment including anti-edema and antiviral therapies.
爱泼斯坦-巴尔病毒感染累及中枢神经系统通常表现为脑膜炎、脑炎或脑脊髓炎,大多呈疾病的急性形式。在慢性活动性感染中,临床情况可能类似于急性感染,也有慢性炎症的表现,如钙化。本报告介绍了一名8岁女性,患有慢性活动性爱泼斯坦-巴尔病毒感染和脑炎,并伴有颅内压升高,通过反复腰椎穿刺及包括抗水肿和抗病毒治疗在内的药物治疗进行管理。