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Antimicrobial Peptides can Enhance the Risk of Persistent Infections.

作者信息

Berditsch Marina, Afonin Sergii, Vladimirova Tatiana, Wadhwani Parvesh, Ulrich Anne S

机构信息

Institute of Organic Chemistry, Karlsruhe Institute of Technology Karlsruhe, Germany.

出版信息

Front Immunol. 2012 Aug 1;3:222. doi: 10.3389/fimmu.2012.00222. eCollection 2012.

DOI:10.3389/fimmu.2012.00222
PMID:22870073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3409353/
Abstract
摘要

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Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH.通过肽 Esculentin-1a(1-21)NH 的选择性差向异构作用抑制铜绿假单胞菌生物膜的形成和毒力基因的表达。
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Synergistic effect of membrane-active peptides polymyxin B and gramicidin S on multidrug-resistant strains and biofilms of Pseudomonas aeruginosa.

本文引用的文献

1
Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly as a β-Barrel.脂质膜中抗菌肽短杆菌肽S的固态核磁共振结构分析:浓度依赖性重新排列和作为β桶的自组装
Top Curr Chem. 2008;273:139-54. doi: 10.1007/128_2007_20.
2
Modulating immunity as a therapy for bacterial infections.调节免疫作为治疗细菌感染的一种方法。
Nat Rev Microbiol. 2012 Mar 16;10(4):243-54. doi: 10.1038/nrmicro2745.
3
Designing antimicrobial peptides: form follows function.设计抗菌肽:形式服从功能。
膜活性肽多粘菌素B和短杆菌肽S对铜绿假单胞菌多重耐药菌株和生物膜的协同作用。
Antimicrob Agents Chemother. 2015 Sep;59(9):5288-96. doi: 10.1128/AAC.00682-15. Epub 2015 Jun 15.
Nat Rev Drug Discov. 2011 Dec 16;11(1):37-51. doi: 10.1038/nrd3591.
4
Antibiotic-induced biofilm formation.抗生素诱导的生物膜形成。
Int J Artif Organs. 2011 Sep;34(9):737-51. doi: 10.5301/ijao.5000027.
5
Deciphering the mode of action of the synthetic antimicrobial peptide Bac8c.解析合成抗菌肽 Bac8c 的作用模式。
Antimicrob Agents Chemother. 2011 Apr;55(4):1706-16. doi: 10.1128/AAC.01053-10. Epub 2011 Jan 31.
6
Topical drug delivery by a polymeric nanosphere gel: Formulation optimization and in vitro and in vivo skin distribution studies.聚合物纳米球凝胶的经皮给药:制剂优化及体外和体内皮肤分布研究。
J Control Release. 2011 Jan 20;149(2):159-67. doi: 10.1016/j.jconrel.2010.10.005. Epub 2010 Oct 13.
7
Resistance to polymyxins: Mechanisms, frequency and treatment options.对多黏菌素的耐药性:机制、频率和治疗选择。
Drug Resist Updat. 2010 Aug-Oct;13(4-5):132-8. doi: 10.1016/j.drup.2010.05.002. Epub 2010 Jun 17.
8
19F NMR analysis of the antimicrobial peptide PGLa bound to native cell membranes from bacterial protoplasts and human erythrocytes.19F NMR 分析抗菌肽 PGLa 与细菌原生质体和人红细胞天然细胞膜的结合。
J Am Chem Soc. 2010 Jul 7;132(26):8822-4. doi: 10.1021/ja101608z.
9
Damage of the bacterial cell envelope by antimicrobial peptides gramicidin S and PGLa as revealed by transmission and scanning electron microscopy.抗菌肽短杆菌素 S 和 PGLa 通过透射和扫描电子显微镜揭示的细菌细胞包膜损伤。
Antimicrob Agents Chemother. 2010 Aug;54(8):3132-42. doi: 10.1128/AAC.00124-10. Epub 2010 Jun 7.
10
Persister cells.持留细胞。
Annu Rev Microbiol. 2010;64:357-72. doi: 10.1146/annurev.micro.112408.134306.