基于适体的 ATP 检测引发的 GOx 信号转导。
GOx signaling triggered by aptamer-based ATP detection.
机构信息
Department of Chemistry, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, LA 70125, USA.
出版信息
Chem Commun (Camb). 2012 Sep 25;48(74):9284-6. doi: 10.1039/c2cc34279k. Epub 2012 Aug 9.
Abstract
Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to 'turn-on' the activity of apo-GOx and thus generates a measurable response.
摘要
适配体结合 ATP 会导致辅因子 FAD 的释放，FAD 作为一个触发物“开启”apo-GOx 的活性，从而产生可测量的响应。
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