Department of Orthopaedic Surgery, University of Southern California, Keck School of Medicine, 711 West College Street, Suite 625, Los Angeles, CA 90012, USA.
Eur Spine J. 2013 Feb;22(2):439-45. doi: 10.1007/s00586-012-2458-x. Epub 2012 Aug 10.
To investigate if instrumentation (unilateral vs. bilateral fixation) has an effect on the rate of fusion cage migration.
This clinical study of transforaminal lumbar interbody fusion involved a prospective group of 116 patients who were randomly assigned to either unilateral (n = 57) or bilateral (n = 59) fixation. Fourteen were lost to follow-up (11 from the unilateral group and 3 from the bilateral group).
The unilateral fixation group consisted of 20 male and 26 female patients. In the unilateral group, the mean age was 53.5 years (range, 18-77), and the preoperative diagnosis consisted of degenerative disc disease, with or without herniated disc (n = 44), and degenerative spondylolisthesis with spinal stenosis (n = 2). The bilateral fixation group consisted of 20 male and 36 female patients. In the bilateral group, the mean age was 55.7 years (range, 26-82), and the preoperative diagnosis consisted of degenerative disc disease, with or without herniated disc (n = 40), and degenerative spondylolisthesis with spinal stenosis (n = 16). A total of 17 cases of cage migration were found; of these, 11 were from the unilateral group and 6 from the bilateral group, resulting in rates of cage migration of 23 and 11 % (p = 0.03), respectively. In regard to migration cases, 5 were male and 12 were female. Ages ranged from 27 to 79 years (mean age, 55 years).
We conclude that unilateral fixation is not stable enough to prevent fusion cage migration in some patients who undergo TLIF.
研究器械固定(单侧与双侧固定)是否会影响融合 cage 迁移率。
本研究为经椎间孔腰椎体间融合术的临床研究,共纳入 116 例患者,采用前瞻性分组,随机分为单侧固定组(n=57)和双侧固定组(n=59)。随访中丢失 14 例(单侧组 11 例,双侧组 3 例)。
单侧固定组 57 例患者中,男 20 例,女 26 例。单侧组平均年龄为 53.5 岁(18-77 岁),术前诊断为退行性椎间盘疾病,伴或不伴椎间盘突出(n=44),退行性脊柱滑脱伴椎管狭窄(n=2)。双侧固定组 59 例患者中,男 20 例,女 36 例。双侧组平均年龄为 55.7 岁(26-82 岁),术前诊断为退行性椎间盘疾病,伴或不伴椎间盘突出(n=40),退行性脊柱滑脱伴椎管狭窄(n=16)。共发现 17 例 cage 迁移,其中单侧组 11 例,双侧组 6 例,分别为 23%和 11%(p=0.03)。在迁移病例中,男 5 例,女 12 例。年龄 27-79 岁,平均 55 岁。
我们认为在一些接受 TLIF 的患者中,单侧固定不足以防止融合 cage 迁移。