Yassi Annalee, O'Hara Lyndsay M, Lockhart Karen, Spiegel Jerry M
School of Population and Public Health, The University of British Columbia, Vancouver, BC, Canada.
AIDS Care. 2013;25(5):525-43. doi: 10.1080/09540121.2012.712668. Epub 2012 Aug 13.
The health service sector has a vital role to play in delivering human immunodeficiency virus (HIV) and tuberculosis (TB) prevention, treatment and care, yet evidence indicates that healthcare workers (HCWs) themselves lack adequate access to HIV and TB services. HCWs are also at increased risk from TB and other infectious diseases at work, and therefore accessing HIV services is particularly important. A systematic review was therefore conducted to inform the development of World Health Organization (WHO) guidelines to improve access to HIV and TB services, and specifically, to assess the evidence regarding providing such services through workplace-based programmes. We identified any study published since 1984 that addressed outcomes of interest as defined through multi-stakeholder consultations, and were related to workplace interventions in (1) the healthcare workplace and (2) any workplace that included HIV and/or TB diagnosis and/or treatment. Interventions focusing solely on primary prevention with no diagnostic or treatment services were excluded, as they were the subject of other guidelines. A minimum of two reviewers independently extracted data and assessed the articles against pre-set selection criteria; studies were also profiled and quality assessed by a minimum of two reviewers. Three studies met these criteria specifically for HCWs; all showed a preponderance of positive benefits, with minimal negative outcome. Seven studies met these criteria regarding workplace HIV and/or TB diagnosis and/or treatment from other sectors, public or private. Again, all showed positive results. The paucity of high-quality evidence in this field of research was itself an important finding, beckoning further research on workplace-based programmes for health workers. Nonetheless, while more well-designed intervention studies are definitely desirable, providing programmes for HCWs to obtain HIV and TB diagnosis and treatment at the workplace is supported by the literature and is consistent with the values of the stakeholders, justifying the WHO-International Labour Organization-UNAIDS guidelines that emerged.
卫生服务部门在提供人类免疫缺陷病毒(HIV)和结核病(TB)的预防、治疗及护理方面发挥着至关重要的作用,但有证据表明医护人员自身却无法充分获得HIV和TB服务。医护人员在工作中感染结核病和其他传染病的风险也有所增加,因此获得HIV服务尤为重要。因此,开展了一项系统综述,以为世界卫生组织(WHO)制定改善HIV和TB服务可及性的指南提供信息,具体而言,是为了评估通过基于工作场所的项目提供此类服务的证据。我们检索了自1984年以来发表的任何研究,这些研究涉及通过多利益相关方协商确定的感兴趣的结果,并且与(1)医疗工作场所和(2)任何包括HIV和/或TB诊断和/或治疗的工作场所的工作场所干预措施相关。仅专注于一级预防而无诊断或治疗服务的干预措施被排除在外,因为它们是其他指南的主题。至少两名评审员独立提取数据,并根据预先设定的选择标准评估文章;研究还由至少两名评审员进行了描述和质量评估。三项研究专门针对医护人员符合这些标准;所有研究均显示出大量的积极益处,负面结果极少。七项研究符合关于其他公共或私营部门工作场所HIV和/或TB诊断和/或治疗的这些标准。同样,所有研究均显示出积极结果。该研究领域高质量证据的匮乏本身就是一个重要发现,促使人们对针对卫生工作者的基于工作场所的项目进行进一步研究尽管无疑更需要设计更完善的干预研究,但文献支持为医护人员提供在工作场所获得HIV和TB诊断及治疗的项目,并且这与利益相关方的价值观一致,这证明了已出台的WHO-国际劳工组织-联合国艾滋病规划署指南的合理性。