Intellectual Disability Medicine, Department of General Practice, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
J Affect Disord. 2013 Jan 10;144(1-2):94-100. doi: 10.1016/j.jad.2012.06.011. Epub 2012 Aug 9.
Little is known about the prevalence of depression and anxiety among older people with intellectual disabilities (ID). Therefore, the aim of this study was to study the prevalence of depression and anxiety in this population.
This study is a cross-sectional epidemiologic multicentre study which was part of the "Healthy Ageing and Intellectual Disabilities" study. The study population consisted of 990 participants aged ≥50 years with borderline to profound ID which were screened with self-report and informant-report instruments; 290 of them were assessed with a standardized diagnostic interview.
Depressive symptoms were prevalent in 16.8% (95% CI: 14.4-19.1) and significantly associated with higher age. Anxiety symptoms were prevalent in 16.3% (95% CI: 14.0-18.6) and significantly associated with female gender and borderline to mild ID. Major depressive disorder was prevalent in 7.6% (95% CI: 5.2-11.0), anxiety disorders in 4.4% (95% CI: 2.6-7.0) and both in 0.7% (95% CI: 0.2-1.6). There was no relationship with gender, age or level of ID.
For most participants, informant-report instruments have been used instead of self-report to overcome communication difficulties or inabilities. Also, a standardized psychiatric diagnostic interview has been used instead of psychiatric diagnoses made by an experienced psychiatrist.
Prevalence of major depressive disorder is higher and of anxiety disorders lower than in the Dutch general older community-dwelling population.
关于智力障碍（ID）老年人中抑郁和焦虑的患病率知之甚少。因此，本研究旨在研究该人群中抑郁和焦虑的患病率。
这是一项横断面的、多中心的、流行病学研究，是“健康老龄化与智力障碍”研究的一部分。研究人群由 990 名年龄≥50 岁、有边缘至严重 ID 的人组成，他们通过自我报告和知情者报告工具进行筛查；其中 290 人接受了标准化的诊断访谈。
抑郁症状的患病率为 16.8%（95%可信区间：14.4-19.1），且与较高的年龄显著相关。焦虑症状的患病率为 16.3%（95%可信区间：14.0-18.6），且与女性性别和边缘至轻度 ID 显著相关。重度抑郁症的患病率为 7.6%（95%可信区间：5.2-11.0），焦虑障碍的患病率为 4.4%（95%可信区间：2.6-7.0），两者的患病率为 0.7%（95%可信区间：0.2-1.6）。与性别、年龄或 ID 水平无关。
对于大多数参与者，使用知情者报告工具代替自我报告来克服沟通困难或无法报告。此外，使用标准化的精神病学诊断访谈代替由经验丰富的精神科医生做出的精神病学诊断。
重度抑郁症的患病率高于荷兰一般社区居住的老年人群，而焦虑症的患病率则较低。
