健康老龄化和智力残疾研究:发现总结及 10 年随访研究方案。

Healthy Ageing and Intellectual Disability study: summary of findings and the protocol for the 10-year follow-up study.

机构信息

Department of General Practice, Intellectual Disability Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands

Department of General Practice, Intellectual Disability Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands.

出版信息

BMJ Open. 2022 Feb 22;12(2):e053499. doi: 10.1136/bmjopen-2021-053499.

Abstract

INTRODUCTION

The Healthy Ageing and Intellectual Disability (HA-ID) study is a prospective multicentre cohort study in the Netherlands that started in 2008, including 1050 older adults (aged ≥50) with intellectual disabilities (ID). The study is designed to learn more about the health and health risks of this group as they age. Compared with the amount of research in the general population, epidemiological research into the health of older adults with ID is still in its infancy. Longitudinal data about the health of this vulnerable and relatively unhealthy group are needed so that policy and care can be prioritised and for guiding clinical decision making about screening, prevention and treatment to improve healthy ageing.

METHODS AND ANALYSIS

This article presents a summary of the previous findings of the HA-ID study and describes the design of the 10-year follow-up in which a wide range of health data will be collected within five research themes: (1) cardiovascular disease; (2) physical activity, fitness and musculoskeletal disorders; (3) psychological problems and psychiatric disorders; (4) nutrition and nutritional state; and (5) frailty.

ETHICS AND DISSEMINATION

Ethical approval for the 10-year follow-up measurements of the HA-ID study has been obtained from the Medical Ethics Review Committee of the Erasmus MC, University Medical Centre Rotterdam (MEC-2019-0562).

TRIAL REGISTRATION NUMBER

This cohort study is registered in the Dutch Trial Register (NTR number NL8564) and has been conducted according to the principles of the Declaration of Helsinki.

摘要

简介

健康老龄化与智力障碍(HA-ID)研究是一项始于 2008 年的荷兰前瞻性多中心队列研究,纳入了 1050 名年龄≥50 岁的智力障碍(ID)成年人。该研究旨在深入了解这一人群随着年龄增长的健康状况和健康风险。与普通人群的研究相比,针对智力障碍老年人健康的流行病学研究仍处于起步阶段。需要获得有关这一弱势群体和相对不健康群体健康状况的纵向数据,以便为政策和护理提供优先重点,并为改善健康老龄化的筛查、预防和治疗提供指导临床决策。

方法与分析

本文总结了 HA-ID 研究的先前发现,并描述了 10 年随访的设计,其中将在五个研究主题中收集广泛的健康数据:(1)心血管疾病;(2)身体活动、健身和肌肉骨骼疾病;(3)心理问题和精神障碍;(4)营养和营养状况;以及(5)虚弱。

伦理与传播

HA-ID 研究的 10 年随访测量已获得鹿特丹伊拉斯姆斯医学中心 Erasmus MC 医学伦理审查委员会(MEC-2019-0562)的伦理批准。

试验注册号

本队列研究已在荷兰试验注册处(NTR 编号 NL8564)注册,并根据《赫尔辛基宣言》的原则进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ff/8867312/6d29d9993220/bmjopen-2021-053499f01.jpg

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