Nazarov I P, Ianitskiĭ A V, Popov A A, Bukhanistyĭ V P, Voloshenko E V
Anesteziol Reanimatol. 1990 Sep-Oct(5):76-8.
Central and peripheral hemodynamic changes have been studied in 80 patients aged 18 to 67 years after planned gastro-intestinal and biliary surgery. In 40 of them clopheline (clonidine) was used in premedication. The use of clopheline in premedication led to stabilization of central hemodynamic parameters, made it possible to improve considerably microcirculation, avoid the unfavourable effects of psychic tension, induction to anesthesia, laryngoscopy and tracheal intubation. All the above permits the authors to recommend the use of clopheline in premedication.
对80例年龄在18至67岁之间接受计划性胃肠和胆道手术的患者进行了中心和外周血流动力学变化的研究。其中40例患者在术前用药中使用了可乐定。术前使用可乐定可使中心血流动力学参数稳定，能显著改善微循环，避免精神紧张、诱导麻醉、喉镜检查和气管插管的不利影响。基于上述所有情况，作者推荐在术前用药中使用可乐定。
