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软珊瑚 Sarcophyton glaucum 中的新四萜前体。

New precursor of tetraterpenoids from the soft coral Sarcophyton glaucum.

机构信息

School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, PR China.

出版信息

Nat Prod Res. 2013;27(9):782-6. doi: 10.1080/14786419.2012.701211. Epub 2012 Jul 2.

Abstract

One new precursor of tetraterpenoids, Sarglaucol (1), along with eight known compounds have been isolated from the soft coral Sarcophyton glaucum collected from the Sanya Bay, Hainan Island, China. Their structures were elucidated through spectroscopic techniques including 1D- and 2D-NMR, and their relative configurations were also assigned by NMR and NOESY analysis. Compounds 1 showed weak antitumour activities.

摘要

从中国海南岛三亚湾采集的软珊瑚 Sarcophyton glaucum 中分离得到一种新的四萜前体 Sarglaucol(1)和 8 种已知化合物。通过包括 1D-和 2D-NMR 在内的光谱技术阐明了它们的结构,并且通过 NMR 和 NOESY 分析还确定了它们的相对构型。化合物 1 表现出较弱的抗肿瘤活性。

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