来自软珊瑚灰叶肉芝的类异戊二烯。
Isoprenoids from the Soft Coral Sarcophyton glaucum.
作者信息
Chao Chih-Hua, Li Wen-Liang, Huang Chiung-Yao, Ahmed Atallah F, Dai Chang-Feng, Wu Yang-Chang, Lu Mei-Chin, Liaw Chih-Chuang, Sheu Jyh-Horng
机构信息
School of Pharmacy, China Medical University, Taichung 404, Taiwan.
Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan.
出版信息
Mar Drugs. 2017 Jun 27;15(7):202. doi: 10.3390/md15070202.
Five new isoprenoids, 3,4,8,16-tetra--lobocrasol (), 1,15β-epoxy-deoxysarcophine (), 3,4-dihydro-4α,7β,8α-trihydroxy-Δ²-sarcophine (3), -sarcophyolide E (4), and 16-deacetyl- halicrasterol B (5) and ten known compounds 6‒, were characterized from the marine soft coral , collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The structure of the known compound lobocrasol () was revised. Cytotoxicity potential of the isolated compounds was reported, too.
从台东海岸线附近采集的海洋软珊瑚中鉴定出5种新的类异戊二烯化合物，即3,4,8,16-四-罗布可醇（）、1,15β-环氧-脱氧肉珊瑚碱（）、3,4-二氢-4α,7β,8α-三羟基-Δ²-肉珊瑚碱（3）、-肉珊瑚内酯E（4）和16-脱乙酰-卤代海石甾醇B（5），以及10种已知化合物6‒。通过分析光谱数据，尤其是二维核磁共振（2D NMR）和电子圆二色光谱（ECD）确定了它们的结构。已知化合物罗布可醇（）的结构得到了修正。还报道了分离出的化合物的细胞毒性潜力。
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