Department of Ophthalmology, Charité, University Medicine Berlin, Berlin, Germany.
Ophthalmic Res. 2012;48(4):192-8. doi: 10.1159/000339598. Epub 2012 Aug 3.
Large full-thickness eyelid defects are conventionally reconstructed by either a Hughes flap or Cutler-Beard bridge flap. Since the structure of the eyelid and its components are necessary for the tear film production and stability, we investigated the outcome after eyelid reconstruction focusing on dry eye symptoms using a new thermographic device, the TG-1000.
Seventeen eyes of patients formerly treated with Hughes flaps (n = 16) and a Cutler-Beard bridge flap (n = 1) were compared to untreated healthy eyes (n = 17) regarding the functional and aesthetic outcome. The follow-up ranged from 3 to 63 months (mean 24.88 ± 17.86).
There was no significant difference in Schirmer's test, break-up time and ocular surface temperature (p > 0.05) between patients after full-thickness eyelid reconstruction and a control group. Eleven patients had minor postoperative complications such as notching of the lid margin (11/17), epiphora (1/17), superficial punctate keratitis (6/17), trichiasis (2/17) and a mild tendency to eversion of the lid margin (6/17). More than 75% of the patients rated their postoperative aesthetic outcome as good or even excellent.
The new TG-1000 device is a simple and quick tool for screening of dry eye. This study shows that tarsoconjunctival grafts offer good aesthetic and functional outcome with sufficient tear film composition and stability.
传统上，大面积全层眼睑缺损是通过 Hughes 皮瓣或 Cutler-Beard 桥状皮瓣进行重建的。由于眼睑及其成分的结构对于泪膜的产生和稳定性是必需的，因此我们使用新型热像仪 TG-1000 研究了眼睑重建后与干眼症状相关的结果。
对 16 例 Hughes 皮瓣和 1 例 Cutler-Beard 桥状皮瓣治疗的患者的 17 只眼（n = 17）进行功能和美学结果的评估，并与未治疗的健康眼（n = 17）进行比较。随访时间为 3 至 63 个月（平均 24.88 ± 17.86）。
全层眼睑重建后患者与对照组之间的 Schirmer 试验、泪膜破裂时间和眼表面温度均无显著差异（p > 0.05）。11 例患者有轻微的术后并发症，如睑缘切迹（11/17）、溢泪（1/17）、浅层点状角膜炎（6/17）、倒睫（2/17）和轻度眼睑外翻趋势（6/17）。超过 75%的患者对术后美学效果的评价为良好甚至优秀。
新型 TG-1000 设备是一种简单快速的干眼筛查工具。本研究表明，睑结膜移植物具有良好的美学和功能效果，泪膜组成和稳定性充足。
