Nakayama Satoshi
Department of Gastroenterology, Mishuku Hospital, 5-33-12, Kamimeguro, Meguro-ku, Tokyo, 153-0051, Japan.
Indian J Gastroenterol. 2012 Sep;31(5):267-70. doi: 10.1007/s12664-012-0220-2. Epub 2012 Aug 15.
A 92-year-old Japanese woman with moderate liver fibrosis, schistosomiasis and steatohepatitis-like lesion, was diagnosed with hepatocellular carcinoma (HCC) by dynamic CT and elevated serum levels of alpha-fetoprotein and des-gamma-carboxyprothrombin. During follow up, the levels of tumor markers became normal without any treatment, and dynamic CT showed disappearance of the tumor and progression of hepatic steatosis. The mechanism of this spontaneous regression of HCC is unclear although massive necrosis due to rapid tumor growth or cancer immunity may have played a role.
一名92岁的日本女性，患有中度肝纤维化、血吸虫病和脂肪性肝炎样病变，通过动态CT以及血清甲胎蛋白和异常凝血酶原水平升高被诊断为肝细胞癌（HCC）。在随访期间，未经任何治疗，肿瘤标志物水平恢复正常，动态CT显示肿瘤消失且肝脂肪变性进展。尽管快速肿瘤生长导致的大片坏死或癌症免疫可能起了作用，但HCC这种自发消退的机制尚不清楚。
