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睡眠质量对快速通道腹式子宫切除术康复的影响。

The impact of quality of sleep on recovery from fast-track abdominal hysterectomy.

机构信息

Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, County Council of Östergötland, Sweden.

出版信息

J Clin Sleep Med. 2012 Aug 15;8(4):395-402. doi: 10.5664/jcsm.2032.

Abstract

STUDY OBJECTIVES

To examine the impact of mode of anesthesia on perceived quality of sleep and to analyze the perceived quality of sleep in affecting recovery from surgery.

METHODS

A randomized, controlled, open multicenter trial was conducted in 5 hospitals in Southeast Sweden. One-hundred eighty women scheduled for fast-track abdominal hysterectomy for benign conditions were randomized to spinal anesthesia or general anesthesia; 162 women completed the trial; 82 allocated to spinal anesthesia and 80 to general anesthesia. Symptoms and perceived quality of sleep after surgery were registered daily in the Swedish Postoperative Symptoms Questionnaire.

RESULTS

Women in the general anesthesia group experienced bad quality of sleep the night after surgery significantly more often than the women who had spinal anesthesia (odds ratio [OR] 2.45; p = 0.03). This was almost exclusively attributed to a significantly higher consumption of opioids postoperatively in the general anesthesia group. Risk factors for bad quality of sleep during the first night postoperatively were: opioids (OR 1.07; p = 0.03); rescue antiemetics (OR 2.45; p = 0.05); relative weight gain (OR 1.47; p = 0.04); summary score of postoperative symptoms (OR 1.13; p = 0.02); and stress coping capacity (OR 0.98; p = 0.01). A longer hospital stay was strongly associated with a poorer quality of sleep the first night postoperatively (p = 0.002).

CONCLUSIONS

The quality of sleep the first night after abdominal hysterectomy is an important factor for recovery. In fast-track abdominal hysterectomy, it seems important to use anesthesia and multimodal analgesia reducing the need for opioids postoperatively and to use strategies that diminish other factors that may interfere negatively with sleep. Efforts to enhance quality of sleep postoperatively by means of preventive measures and treatment of sleep disturbances should be included in fast-track programs.

摘要

研究目的

探讨麻醉方式对睡眠质量的影响,并分析睡眠质量对手术恢复的影响。

方法

在瑞典东南部的 5 家医院进行了一项随机、对照、开放的多中心试验。180 名因良性疾病接受快速通道腹部子宫切除术的女性患者被随机分配至脊髓麻醉或全身麻醉组;162 名女性完成了试验;82 名分配至脊髓麻醉组,80 名分配至全身麻醉组。术后每日使用瑞典术后症状问卷登记症状和睡眠质量。

结果

全身麻醉组女性在手术后的第一晚睡眠质量明显差于接受脊髓麻醉的女性(比值比 [OR] 2.45;p = 0.03)。这几乎完全归因于全身麻醉组术后阿片类药物的使用明显增加。术后第一晚睡眠质量差的危险因素包括:阿片类药物(OR 1.07;p = 0.03);解救止吐药(OR 2.45;p = 0.05);相对体重增加(OR 1.47;p = 0.04);术后症状综合评分(OR 1.13;p = 0.02);和应激应对能力(OR 0.98;p = 0.01)。住院时间延长与术后第一晚睡眠质量差密切相关(p = 0.002)。

结论

腹部子宫切除术后第一晚的睡眠质量是恢复的一个重要因素。在快速通道腹部子宫切除术,使用麻醉和多模式镇痛减少术后阿片类药物的需求,以及使用策略减少其他可能对睡眠产生负面影响的因素,似乎很重要。通过预防措施和治疗睡眠障碍来提高术后睡眠质量的努力应包括在快速通道计划中。

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