基于空间和时间调制光的漫射光学成像。
Diffuse optical imaging using spatially and temporally modulated light.
机构信息
University of California, Irvine, Laser Microbeam and Medical Program (LAMMP), Beckman Laser Institute and Medical Clinic, Irvine, California, USA.
出版信息
J Biomed Opt. 2012 Jul;17(7):071311. doi: 10.1117/1.JBO.17.7.071311.
Abstract
The authors describe the development of diffuse optical imaging (DOI) technologies, specifically the use of spatial and temporal modulation to control near infrared light propagation in thick tissues. We present theory and methods of DOI focusing on model-based techniques for quantitative, in vivo measurements of endogenous tissue absorption and scattering properties. We specifically emphasize the common conceptual framework of the scalar photon density wave for both temporal and spatial frequency-domain approaches. After presenting the history, theoretical foundation, and instrumentation related to these methods, we provide a brief review of clinical and preclinical applications from our research as well as our outlook on the future of DOI technology.
摘要
作者描述了漫射光学成像（DOI）技术的发展，特别是利用空间和时间调制来控制近红外光在厚组织中的传播。我们介绍了 DOI 聚焦的理论和方法，重点是基于模型的技术，用于对内源性组织吸收和散射特性进行定量、活体测量。我们特别强调了时间和空间频域方法中普遍存在的标量光子密度波的共同概念框架。在介绍了这些方法的历史、理论基础和仪器设备之后，我们简要回顾了我们的研究中的临床和临床前应用，以及我们对 DOI 技术未来的展望。
相似文献
1
Diffuse optical imaging using spatially and temporally modulated light.基于空间和时间调制光的漫射光学成像。
J Biomed Opt. 2012 Jul;17(7):071311. doi: 10.1117/1.JBO.17.7.071311.
2
Scanless two-photon excitation with temporal focusing.无扫描双光子激发的时聚焦。
Nat Methods. 2020 Jun;17(6):571-581. doi: 10.1038/s41592-020-0795-y. Epub 2020 Apr 13.
3
Imaging autofluorescence temporal signatures of the human ocular fundus in vivo.体内人眼眼底的成像自体荧光时间特征
J Biomed Opt. 2015 Nov;20(11):110505. doi: 10.1117/1.JBO.20.11.110505.
4
Video-rate near-infrared optical tomography using spectrally encoded parallel light delivery.使用光谱编码平行光传输的视频速率近红外光学断层扫描。
Opt Lett. 2005 Oct 1;30(19):2593-5. doi: 10.1364/ol.30.002593.
5
Theory of diffraction effects in spatial frequency-modulated imaging.空间频率调制成像中的衍射效应理论
J Opt Soc Am A Opt Image Sci Vis. 2012 Dec 1;29(12):2579-90. doi: 10.1364/JOSAA.29.002579.
6
Contrast and resolution enhanced optical sectioning in scattering tissue using line-scanning two-photon structured illumination microscopy.使用线扫描双光子结构照明显微镜在散射组织中增强对比度和分辨率的光学切片
Opt Express. 2017 Dec 11;25(25):32010-32020. doi: 10.1364/OE.25.032010.
7
Upconversion fiber-optic confocal microscopy under near-infrared pumping.近红外泵浦下的上转换光纤共聚焦显微镜
Opt Lett. 2008 Mar 1;33(5):425-7. doi: 10.1364/ol.33.000425.
8
Phase retrieval using spatially modulated illumination.使用空间调制照明进行相位恢复。
Opt Lett. 2014 Jun 15;39(12):3615-8. doi: 10.1364/OL.39.003615.
9
Computational phase modulation in light field imaging.光场成像中的计算相位调制
Opt Express. 2013 Dec 2;21(24):29523-43. doi: 10.1364/OE.21.029523.
引用本文的文献
1
Innovative Discrete Multi-Wavelength Near-Infrared Spectroscopic (DMW-NIRS) Imaging for Rapid Breast Lesion Differentiation: Feasibility Study.用于快速乳腺病变鉴别诊断的创新型离散多波长近红外光谱（DMW-NIRS）成像：可行性研究
Diagnostics (Basel). 2025 Apr 23;15(9):1067. doi: 10.3390/diagnostics15091067.
2
Impact of clinical factors on the diagnostic performance of diffuse optical spectroscopic imaging for breast cancer.临床因素对乳腺癌漫射光学光谱成像诊断性能的影响。
Sci Rep. 2025 Apr 25;15(1):14508. doi: 10.1038/s41598-025-98519-6.
3
Monte Carlo Guidance for Better Imaging of Boreal Lakes in the Wavelength Region of 400-800 nm.蒙特卡洛方法在400-800纳米波长区域对北方湖泊进行更好成像的指导
Sensors (Basel). 2025 Feb 9;25(4):1020. doi: 10.3390/s25041020.
4
Rapid diffused optical imaging for accurate 3D estimation of subcutaneous tissue features.用于皮下组织特征精确三维估计的快速扩散光学成像
iScience. 2025 Jan 23;28(2):111818. doi: 10.1016/j.isci.2025.111818. eCollection 2025 Feb 21.
5
Phase-based structured interrogation frequency-domain near-infrared spectroscopy.基于相位的结构化询问频域近红外光谱技术
J Opt Soc Am A Opt Image Sci Vis. 2024 Aug 1;41(8):1500-1512. doi: 10.1364/JOSAA.523194.
6
Emulation of Brain Metabolic Activities Based on a Dynamically Controllable Optical Phantom.基于动态可控光学体模的脑代谢活动模拟
Cyborg Bionic Syst. 2023 Sep 13;4:0047. doi: 10.34133/cbsystems.0047. eCollection 2023.
7
Non-invasive optical and laboratory hematologic biomarkers correlate in patients with sickle cell disease.镰状细胞病患者的非侵入性光学和实验室血液生物标志物具有相关性。
Biomed Opt Express. 2024 Jul 26;15(8):4829-4841. doi: 10.1364/BOE.527770. eCollection 2024 Aug 1.
8
Advances and trends in the application of functional near-infrared spectroscopy for pediatric assessments: a bibliometric analysis.功能近红外光谱在儿科评估中的应用进展与趋势：文献计量分析
Front Neurol. 2024 Sep 6;15:1459214. doi: 10.3389/fneur.2024.1459214. eCollection 2024.
9
Medium-adaptive compressive diffuse optical tomography.中等自适应压缩漫射光学层析成像
Biomed Opt Express. 2024 Aug 8;15(9):5128-5142. doi: 10.1364/BOE.529195. eCollection 2024 Sep 1.
10
Wirelessly Powered Visible Light-Emitting Implant for Surgical Guidance during Lumpectomy.无线供电的用于保乳手术中引导的可见光发光植入物。
Sensors (Basel). 2024 Aug 30;24(17):5639. doi: 10.3390/s24175639.
本文引用的文献
1
Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models.临床前神经胶质瘤模型中原卟啉 IX 荧光的空间频域层析成像。
J Biomed Opt. 2012 May;17(5):056008. doi: 10.1117/1.JBO.17.5.056008.
2
Tissue phantoms in multicenter clinical trials for diffuse optical technologies.用于漫射光学技术的多中心临床试验中的组织体模。
Biomed Opt Express. 2012 May 1;3(5):966-71. doi: 10.1364/BOE.3.000966. Epub 2012 Apr 16.
3
Regional and hemispheric asymmetries of cerebral hemodynamic and oxygen metabolism in newborns.新生儿大脑血液动力学和氧代谢的区域性和半球性不对称。
Cereb Cortex. 2013 Feb;23(2):339-48. doi: 10.1093/cercor/bhs023. Epub 2012 Feb 10.
4
Head-up tilt and hyperventilation produce similar changes in cerebral oxygenation and blood volume: an observational comparison study using frequency-domain near-infrared spectroscopy.头高位倾斜和过度通气在脑氧合和血容量方面产生相似的变化：使用频域近红外光谱的观察性比较研究。
Can J Anaesth. 2012 Apr;59(4):357-65. doi: 10.1007/s12630-011-9662-8. Epub 2012 Jan 11.
5
Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain.通过在空间频域中测定组织光学特性对原卟啉 IX 进行定量荧光成像。
J Biomed Opt. 2011 Dec;16(12):126013. doi: 10.1117/1.3665440.
6
Imaging scattering orientation with spatial frequency domain imaging.利用空间频域成像技术进行成像散射方向分析。
J Biomed Opt. 2011 Dec;16(12):126001. doi: 10.1117/1.3657823.
7
Monitoring the response to primary medical therapy for breast cancer using three- dimensional time-resolved optical mammography.使用三维时分辨光乳腺成像术监测乳腺癌的初始药物治疗反应。
Technol Cancer Res Treat. 2011 Dec;10(6):533-47. doi: 10.1177/153303461101000604.
8
Spatial frequency domain spectroscopy of two layer media.两层介质的空间域光谱学。
J Biomed Opt. 2011 Oct;16(10):107005. doi: 10.1117/1.3640814.
9
Methods in diffuse optical imaging.弥散光学成像方法。
Philos Trans A Math Phys Eng Sci. 2011 Nov 28;369(1955):4558-76. doi: 10.1098/rsta.2011.0311.
10
Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.弥散光学光谱成像与乳腺癌新辅助化疗的最终病理反应相关。
Philos Trans A Math Phys Eng Sci. 2011 Nov 28;369(1955):4512-30. doi: 10.1098/rsta.2011.0279.
Zotero 插件