Division of Health and Nutrition Examination Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland, USA.
Am J Hypertens. 2012 Dec;25(12):1271-8. doi: 10.1038/ajh.2012.120. Epub 2012 Aug 16.
Both abdominal obesity, defined as waist circumference (WC) ≥ 102 cm for men and WC ≥ 88 cm for women and increased body mass index (BMI; kg/m²) are known to be associated with hypertension. The aim of this study was to examine the independent and the combined relationship between abdominal obesity and increased BMI and hypertension by age, race, and gender in a national sample.
This report is based on national level cross-sectional data for adults aged 18 years and older (11,145 participants) from the US National Health and Nutrition Examination Survey (NHANES) 2007-2010.
Abdominal obesity, after adjusting for BMI categories and other covariables, was independently associated with hypertension. That is, survey participants classified as abdominally obese had almost 50% increased odds of being hypertensive (odds ratio (OR) 1.51, 95% confidence interval (CI) 1.27-1.81) after controlling for BMI. After adjusting for covariables, the groups of individuals classified as abdominally obese and normal BMI; as abdominally obese and overweight; and abdominally obese and obese each had a progressive increase in the odds of hypertension when compared with individuals who had a normal BMI and no abdominal obesity (OR 1.81, 95% CI 1.28-2.57, OR 1.87, 95% CI 1.55-2.25, and OR 3.23, 95% CI 2.63-3.96, respectively).
Abdominal obesity is independently associated with hypertension after adjusting for BMI. After adjusting for covariables and parameterizing BMI categories and abdominal obesity the new variable showed a progressive increase in the odds of hypertension. Both BMI and WC should be included in models assessing hypertension risks.
腹部肥胖（男性腰围≥102cm，女性腰围≥88cm）和体重指数（BMI；kg/m²）增加均与高血压有关。本研究旨在通过全国代表性样本，按年龄、种族和性别检查腹部肥胖和 BMI 增加与高血压的独立和联合关系。
本报告基于美国国家健康和营养检查调查（NHANES）2007-2010 年 18 岁及以上成年人的全国性横断面数据（11145 名参与者）。
调整 BMI 类别和其他协变量后，腹部肥胖与高血压独立相关。即，与 BMI 控制后，被归类为腹部肥胖的调查参与者患高血压的几率增加了近 50%（优势比[OR]1.51，95%置信区间[CI]1.27-1.81）。调整协变量后，与 BMI 正常且无腹部肥胖的个体相比，被归类为腹部肥胖和正常 BMI、腹部肥胖和超重、腹部肥胖和肥胖的个体患高血压的几率均呈逐渐增加趋势（OR 1.81，95% CI 1.28-2.57，OR 1.87，95% CI 1.55-2.25，OR 3.23，95% CI 2.63-3.96）。
调整 BMI 后，腹部肥胖与高血压独立相关。调整协变量并参数化 BMI 类别和腹部肥胖后，新变量显示出高血压几率的逐渐增加。在评估高血压风险的模型中，应同时包含 BMI 和 WC。
