Hunan Key Laboratory of Green Packaging and Application of Biological Nanotechnology, Hunan University of Technology, Zhuzhou 412008, PR China.
Nanoscale. 2012 Sep 28;4(19):5840-2. doi: 10.1039/c2nr31497e. Epub 2012 Aug 16.
We have developed a fluorescence quenching based approach using graphene oxide (GO) for rapid detection of miRNAs. This GO-based method has been demonstrated to be highly specific to homogenous miRNAs, and is reverse transcription free which simplifies the detection procedures and reduces the total analysis time and cost.
我们开发了一种基于石墨烯氧化物(GO)的荧光猝灭方法,用于快速检测 microRNA。这种基于 GO 的方法被证明对同质 microRNA 具有高度特异性,并且无需逆转录,简化了检测步骤,降低了总分析时间和成本。