Université Paris Diderot, Sorbonne Paris Cité, Institut des Energies de Demain (IED), Paris, France.
Plant Cell Environ. 2013 Mar;36(3):569-78. doi: 10.1111/j.1365-3040.2012.02596.x. Epub 2012 Sep 7.
Ozone (O(3) ) is an air pollutant with an impact increasingly important in our industrialized world. It affects human health and productivity in various crops. We provide the evidences that treatment of Arabidopsis thaliana with O(3) results in ascorbate-derived oxalic acid production. Using cultured cells of A. thaliana as a model, here we further showed that oxalic acid induces activation of anion channels that trigger depolarization of the cell, increase in cytosolic Ca(2+) concentration, generation of reactive oxygen species and cell death. We confirmed that O(3) reacts with ascorbate in the culture, thus resulting in production of oxalic acid and this could be part of the O(3) -induced signalling pathways that trigger programmed cell death.
臭氧（O3）是一种空气污染物，在我们这个工业化世界中的影响越来越重要。它会影响人类健康和各种农作物的生产力。我们提供的证据表明，用臭氧处理拟南芥会导致抗坏血酸衍生出草酸。在这里，我们使用拟南芥的培养细胞作为模型，进一步表明草酸诱导阴离子通道的激活，从而引发细胞去极化、细胞内 Ca2+浓度增加、活性氧的产生和细胞死亡。我们证实，臭氧在培养物中与抗坏血酸反应，从而产生草酸，这可能是引发程序性细胞死亡的臭氧诱导信号通路的一部分。
