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精神分裂症谱系和情感障碍患者的童年创伤发生率较高。

High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder.

机构信息

Department of Research and Development, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

出版信息

Compr Psychiatry. 2013 Feb;54(2):123-7. doi: 10.1016/j.comppsych.2012.06.009. Epub 2012 Aug 15.

Abstract

OBJECTIVE

Childhood trauma (CT) is a major risk factor for various psychiatric disorders. We wanted to determine the prevalence of CT in a catchment area-based sample of schizophrenia spectrum and affective disorder (including bipolar disorder and depressive episodes with psychotic features) and to explore potential differences in types of CT between the diagnostic groups.

METHOD

Three hundred five patients were recruited consecutively from psychiatric units at 3 major hospitals in Oslo, Norway, diagnosed with Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Traumatic childhood events were assessed with Childhood Trauma Questionnaire.

RESULTS

Eighty-two percent of the patients had experienced one or more CT events, the most frequent subtype of trauma being emotional neglect. The schizophrenia spectrum group reported significantly more physical abuse and physical neglect than the affective group.

CONCLUSION

A high prevalence of CT in patients with severe mental disorder was detected. This reminds us of the importance of exploring this issue when we treat such patients. The mechanisms behind these differences are unclear. Further research is needed to study potential associations between CT and the clinical picture of the disorder.

摘要

目的

儿童期创伤(CT)是各种精神障碍的一个主要危险因素。我们想确定基于抽样的精神分裂症谱系和情感障碍(包括双相情感障碍和伴有精神病特征的抑郁发作)患者中 CT 的患病率,并探讨诊断组之间 CT 类型的潜在差异。

方法

305 名患者连续从挪威奥斯陆 3 家大医院的精神病病房招募,使用精神疾病诊断与统计手册第四版的结构临床访谈进行诊断。使用儿童期创伤问卷评估儿童期创伤事件。

结果

82%的患者经历过一次或多次 CT 事件,最常见的创伤亚型是情感忽视。精神分裂症谱系组报告的身体虐待和身体忽视明显多于情感障碍组。

结论

在严重精神障碍患者中检测到 CT 的高患病率。这提醒我们在治疗此类患者时要探讨这个问题的重要性。这些差异背后的机制尚不清楚。需要进一步研究以研究 CT 与疾病临床特征之间的潜在关联。

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