Department of Nutrition, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, CB# 7400, Chapel Hill, NC 27599-7400, USA.
Nutr Metab Cardiovasc Dis. 2012 Oct;22(10):765-9. doi: 10.1016/j.numecd.2012.03.011. Epub 2012 Aug 15.
The purpose of this paper is to provide a general framework for thinking about pathways and potential mechanisms through which complementary feeding may influence the risk of developing non-communicable diseases (NCDs).
To provide a context for the lack of clear and consistent evidence relating complementary feeding to NCD risk, methodological challenges faced in trying to develop an evidence base are described. Potential pathways through which complementary feeding may influence obesity-related NCD risk are described and illustrated with examples.
Numerous aspects of complementary feeding, including diet composition as well as patterns of feeding have the potential to influence the early development of obesity, which in turn predicts later obesity and NCD risk. Specific dietary exposures during the period of complementary feeding also have the potential to program future disease risk through pathways that are independent of adiposity. These factors all require consideration when making recommendations for optimal complementary feeding practices aimed at prevention of future NCDs.
本文旨在提供一个思考途径和潜在机制的框架,这些途径和机制可能会影响补充喂养对非传染性疾病(NCD)风险的影响。
为了说明缺乏明确和一致的证据表明补充喂养与 NCD 风险之间的关系,本文描述了在试图建立证据基础时所面临的方法学挑战。本文还描述了补充喂养可能影响与肥胖相关的 NCD 风险的潜在途径,并举例说明了这些途径。
补充喂养的许多方面,包括饮食组成以及喂养模式,都有可能影响肥胖的早期发展,而肥胖又会预测以后的肥胖和 NCD 风险。在补充喂养期间的特定饮食暴露也有可能通过与肥胖无关的途径来规划未来的疾病风险。在提出针对未来 NCD 的最佳补充喂养实践建议时,所有这些因素都需要考虑。