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草药医学:在预约门诊麻醉的尼日利亚术前患者中使用情况的调查。

Herbal medicine: a survey of use in Nigerian presurgical patients booked for ambulatory anaesthesia.

机构信息

Department of Anaesthesia, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, PMB 01129, Nigeria.

出版信息

BMC Complement Altern Med. 2012 Aug 20;12:130. doi: 10.1186/1472-6882-12-130.

Abstract

BACKGROUND

Utilization of herbal medicines in the preoperative period by Nigerian patients booked for day case surgery has not been explored.

METHODS

Cross-sectional survey of 60 patients presenting for day-case surgery at a tertiary healthcare institution over a 3-week period in August 2011 was conducted. Using a structured questionnaire, inquiries were made concerning use of herbal medicines in the immediate preoperative period. Socio-demographic characteristics, information on use of concurrent medical prescriptions, types of herbs used, reasons for use, perceived side effects and perceived efficacy were obtained. Data were evaluated using descriptive statistics and Chi-square.

RESULTS

Fifty-two (86.7%) were American Society of Anesthesiologists (ASA) class 1 while 8 (13%) were ASA 2. Most patients (86.7%) had their procedures done under local infiltration with monitored anaesthesia care (MAC), while 5.0% and 8.3% had their procedures done under regional and general anaesthesia, respectively. About 48.3% of respondents were on concurrent medical prescriptions while 51.7% were not. Forty percent (40%) of patients admitted to use of herbal medicine, all by the oral route, in the immediate perioperative period; 87.5% did not inform their doctor of their herbal use. Types of herbs used included 'dogonyaro', 'agbo', 'nchanwu', and Tahitian noni. Treatment of malaria was commonest reason for use in 29.2% of patients, while cough and concurrent surgical condition were reasons given by 12.5% of patients, respectively. Seventy-nine percent (79.2%) of patients considered their herbal medications effective. Perceived side effects of herbal medication (16.6%) included fever, waist pain and intoxication. There were no variations in use between ASA 1 and ASA 2 patients and none between respondents on conventional medication against those that were not. Variables such as age less than 35 years, female gender, being married and being an urban dweller did not show any significant difference in use.

CONCLUSION

This survey revealed many patients were on one or more herbal preparations in the immediate preoperative period. In consideration of possible untoward drug interactions between conventional medication, herbal preparations and anaesthesia, doctors (especially anaesthetists) should routinely assess all patients booked to be anaesthetized, especially those for day case surgery. The authors recommend surveys with larger respondent numbers to determine prevalence of use and possible interactions between indigenous Nigerian herbs and anaesthesia.

摘要

背景

在尼日利亚,行择期日间手术的患者在术前使用草药的情况尚未得到探索。

方法

2011 年 8 月,在一家三级医疗机构对 60 例行日间手术的患者进行了为期 3 周的横断面调查。使用结构化问卷,就患者在术前即刻使用草药的情况进行询问。获取患者的社会人口统计学特征、同时使用的处方药信息、使用的草药类型、使用原因、感知的副作用和感知的疗效等信息。使用描述性统计和卡方检验对数据进行评估。

结果

52 例(86.7%)患者为美国麻醉医师协会(ASA)1 级,8 例(13%)为 ASA 2 级。大多数患者(86.7%)在局部浸润麻醉加监测麻醉护理(MAC)下进行手术,5.0%和 8.3%的患者分别在区域麻醉和全身麻醉下进行手术。约 48.3%的受访者同时服用处方药,而 51.7%的受访者未服用。40%(40%)的患者承认在围手术期内使用了草药,均通过口服途径,87.5%的患者未将其草药使用情况告知医生。使用的草药类型包括“dogonyaro”、“agbo”、“nchanwu”和塔希提诺丽果。29.2%的患者使用草药的最常见原因是治疗疟疾,12.5%的患者因咳嗽和同时存在的手术情况使用草药。79%(79.2%)的患者认为其草药治疗有效。对草药药物的感知副作用(16.6%)包括发热、腰痛和中毒。ASA 1 级和 ASA 2 级患者之间以及同时服用常规药物和未服用常规药物的患者之间,使用情况无差异。年龄小于 35 岁、女性、已婚和居住在城市等变量在使用情况方面没有显示出任何显著差异。

结论

本调查显示,许多患者在术前即刻使用一种或多种草药制剂。鉴于常规药物、草药制剂和麻醉之间可能发生不良的药物相互作用,医生(尤其是麻醉师)应常规评估所有拟接受麻醉的患者,尤其是行日间手术的患者。作者建议进行具有更大样本量的调查,以确定尼日利亚本土草药的使用情况和可能与麻醉相关的相互作用。

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