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一名患有凝血酶原基因突变的患者在腹腔镜胆囊切除术后发生门静脉系统血栓形成。

Thrombosis of portal venous system after laparoscopic cholecystectomy in a patient with prothrombin gene mutation.

作者信息

Gul Waheed, Abbass Khurram, Qazi Arif M, Markert Ronald J, Barde Christopher J

机构信息

Wright State University, Boonshoft School of Medicine, Dayton, OH, USA.

出版信息

JSLS. 2012 Jan-Mar;16(1):166-8. doi: 10.4293/108680812X13291597716663.

DOI:10.4293/108680812X13291597716663
PMID:22906349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3407442/
Abstract

Laparoscopic cholecystectomy is now the gold standard for the treatment of symptomatic cholelithiasis. Portal venous thrombosis after laparoscopic cholecystectomy is rare. We report a case of thrombosis of the portal venous system after laparoscopic cholecystectomy in a patient with a latent prothrombin gene mutation. An abdominal computed tomography and magnetic resonance angiogram of the abdomen revealed portal, superior mesenteric, and splenic vein thrombosis. Testing for coagulation disorders showed a heterozygous form of factor II (prothrombin) G20210A mutation. Because of its rarity, information regarding this complication is limited.

摘要

腹腔镜胆囊切除术现已成为治疗有症状胆结石的金标准。腹腔镜胆囊切除术后门静脉血栓形成较为罕见。我们报告一例在患有潜在凝血酶原基因突变的患者中,腹腔镜胆囊切除术后发生门静脉系统血栓形成的病例。腹部计算机断层扫描和腹部磁共振血管造影显示门静脉、肠系膜上静脉和脾静脉血栓形成。凝血功能障碍检测显示为凝血因子II(凝血酶原)G20210A杂合突变型。由于其罕见性,关于这种并发症的信息有限。

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Portomesenteric venous thrombosis after laparoscopic surgery: a systematic literature review.腹腔镜手术后门静脉肠系膜静脉血栓形成:一项系统文献综述。
Arch Surg. 2009 Jun;144(6):520-6. doi: 10.1001/archsurg.2009.81.
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Unusual cause of pain in abdomen after laparoscopic cholecystectomy.腹腔镜胆囊切除术后腹部疼痛的罕见原因。
Indian J Gastroenterol. 2008 Jan-Feb;27(1):37-8.
3
Portal vein thrombosis: an unusual complication of laparoscopic cholecystectomy.门静脉血栓形成:腹腔镜胆囊切除术的一种罕见并发症。
活体肝移植供体中因子Ⅴ和因子Ⅱ杂合子阳性与并发症
North Clin Istanb. 2023 Sep 26;10(5):550-555. doi: 10.14744/nci.2023.49354. eCollection 2023.
4
Prothrombin Gene Mutation as a Teaching Tool: An Autobiographical Case Report.凝血酶原基因突变作为一种教学工具:一份自传体病例报告。
Cureus. 2023 Jan 19;15(1):e33967. doi: 10.7759/cureus.33967. eCollection 2023 Jan.
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A Rare Case of Portal Vein Thrombosis Following a Successful Laparoscopic Cholecystectomy.腹腔镜胆囊切除术后门静脉血栓形成1例罕见病例
Cureus. 2022 Oct 14;14(10):e30294. doi: 10.7759/cureus.30294. eCollection 2022 Oct.
6
Thrombosis of the spleno-mesentiric portal axis following laparoscopic sleeve gastrectomy: A rare case report.腹腔镜袖状胃切除术后脾-肠系膜门静脉轴血栓形成:一例罕见病例报告
Int J Surg Case Rep. 2018;43:29-31. doi: 10.1016/j.ijscr.2018.02.007. Epub 2018 Feb 9.
7
Acute Portomesenteric Venous Thrombosis following Laparoscopic Small Bowel Resection and Ventral Hernia Repair.腹腔镜小肠切除和腹疝修补术后急性门静脉肠系膜静脉血栓形成
Case Rep Gastrointest Med. 2015;2015:851852. doi: 10.1155/2015/851852. Epub 2015 Aug 3.
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Hepatology. 2000 Mar;31(3):587-91. doi: 10.1002/hep.510310307.