肠球菌中 tet(S) 基因的不同遗传支持。
Different genetic supports for the tet(S) gene in Enterococci.
机构信息
REQUIMTE, Faculdade Farmácia. Universidade do Porto, Porto, Portugal.
出版信息
Antimicrob Agents Chemother. 2012 Nov;56(11):6014-8. doi: 10.1128/AAC.00758-12. Epub 2012 Aug 20.
Abstract
The diversity of tet(S) genetic contexts of 13 enterococci from human, animal, and environmental samples from different geographical areas is reported. The tet(S) gene was linked to either CTn6000 variants of chromosomal location or composite platforms flanked by IS1216 located on plasmids (∼40 to 115 kb). The comparative analysis of all tet(S) genetic elements available in the GenBank databases suggests that CTn6000 might be the origin of a variety of tet(S)-carrying platforms that were mobilized to different plasmids.
摘要
本文报道了来自不同地理区域的人类、动物和环境样本中的 13 株肠球菌中 tet(S)基因的遗传结构多样性。tet(S)基因位于 CTn6000 变体或由位于质粒上的 IS1216 侧翼的复合平台（约 40 到 115kb）。对 GenBank 数据库中所有可用的 tet(S)遗传元件的比较分析表明，CTn6000 可能是多种携带 tet(S)的载体平台的起源，这些平台被转移到不同的质粒上。
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