马黛茶消费与口腔癌风险：乌拉圭病例对照研究。
Maté consumption and risk of oral cancer: Case-control study in Uruguay.
机构信息
Epidemiology Group, Department of Pathology, School of Medicine, Uruguay.
出版信息
Head Neck. 2013 Aug;35(8):1091-5. doi: 10.1002/hed.23080. Epub 2012 Aug 23.
BACKGROUND
In the period 1990 to 2001, a case-control study on oral cancer and maté consumption was conducted at the Cancer Institute of Uruguay.
METHODS
The study included 696 newly diagnosed cases with squamous cell carcinoma and 696 controls afflicted with nonneoplastic conditions not related to tobacco smoking and alcohol drinking. The participants were matched on age and residence and the study was restricted to men.
RESULTS
In order to control confounding for tobacco and alcohol, we fitted 2 models. According to model 1, the odds ratio (OR) for maté consumption was 1.15 (95% confidence interval [CI], 0.76-1.73), whereas the results for model 2 showed an OR of 3.47 (95% CI, 1.60-7.52).
CONCLUSIONS
The inclusion of a term for the interaction between maté and smoking (or drinking) was rewarding and the ORs were even higher than those observed with the crude estimates.
背景
1990 年至 2001 年期间，乌拉圭癌症研究所进行了一项口腔癌与马黛茶消费的病例对照研究。
方法
该研究纳入了 696 例新诊断的鳞状细胞癌病例和 696 例非肿瘤性疾病对照，这些对照不与吸烟和饮酒有关。参与者按照年龄和居住地进行匹配，且该研究仅限于男性。
结果
为了控制烟草和酒精的混杂因素，我们拟合了 2 个模型。根据模型 1，马黛茶消费的比值比（OR）为 1.15（95%置信区间[CI]，0.76-1.73），而模型 2 的结果显示 OR 为 3.47（95% CI，1.60-7.52）。
结论
纳入马黛茶与吸烟（或饮酒）之间相互作用的术语是有益的，而且比值比甚至高于粗估计值观察到的结果。
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