Jaffery Zehra, Prasad Amit, Lee John H, White Christopher J
Department of Cardiovascular Diseases, The John Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, New Orleans, LA, USA.
Patient Relat Outcome Meas. 2011 Jul;2:161-74. doi: 10.2147/PROM.S24796. Epub 2011 Sep 22.
The development of stent has been a major advance in the treatment of obstructive coronary artery disease since the introduction of balloon angioplasty. Subsequently, neointimal hyperplasia within the stent leading to in-stent restenosis emerged as a major obstacle in long-term success of percutaneous coronary intervention. Recent introduction of drug-eluting stents is a major breakthrough to tackle this problem. This review article summarizes stent technology, reviews progress of drug-eluting stents and discusses quality of life, patient satisfaction, and acceptability of percutaneous coronary intervention.
自球囊血管成形术问世以来，支架的发展一直是阻塞性冠状动脉疾病治疗的一项重大进展。随后，支架内新生内膜增生导致支架内再狭窄成为经皮冠状动脉介入治疗长期成功的主要障碍。近期药物洗脱支架的引入是解决这一问题的重大突破。这篇综述文章总结了支架技术，回顾了药物洗脱支架的进展，并讨论了经皮冠状动脉介入治疗的生活质量、患者满意度和可接受性。
