Lobzhanidze A A, Lesnikov V A, Isaeva E N
Biull Eksp Biol Med. 1990 Aug;110(8):182-5.
Experiments on mice (CBA X C57 Bl6)F1 using endo- and exogenous cloning have shown that ultraviolet irradiation of blood enhances colony stimulating properties of plasma. Stimulation of colony formation occurs both in vitro, on direct contact of UV-irradiated blood plasma with bone marrow cells, and in vivo, upon this injection to the whole organism. In the latter case, increased migration of colony forming hematopoietic cells from the bone marrow can be noted. Single intravenous injection of syngenic UV-irradiated blood prevents inhibition of hematopoietic function of the bone marrow induced by closed brain injury.
使用内源性和外源性克隆对(CBA×C57 Bl6)F1小鼠进行的实验表明,血液的紫外线照射可增强血浆的集落刺激特性。集落形成的刺激在体外,即紫外线照射的血浆与骨髓细胞直接接触时发生,也在体内,即在将其注射到整个生物体时发生。在后一种情况下,可以注意到集落形成造血细胞从骨髓的迁移增加。单次静脉注射同基因紫外线照射的血液可防止闭合性脑损伤诱导的骨髓造血功能抑制。