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房颤导管消融中碎裂电位的消融：我们走过了哪些历程，又将走向何方？

Ablation of complex fractionated atrial electrograms in catheter ablation for AF; where have we been and where are we going?

作者信息

Caldwell Jane, Redfearn Damian

机构信息

Arrhythmia Service, Division of Cardiology, Kingston General Hospital, Queen's University, 76 Stuart St, Kingston, Ontario, Canada.

出版信息

Curr Cardiol Rev. 2012 Nov;8(4):347-53. doi: 10.2174/157340312803760848.

DOI:10.2174/157340312803760848
PMID:22920481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3492817/
Abstract

Catheter ablation for persistent AF remains a challenge to the ablator as the disease is now outside the veins and cannot be tackled by pulmonary vein isolation alone. In this article we describe targeting complex fractionated atrial electrograms (CFAE) as a method to guide atrial substrate modification.

摘要

对于持续性房颤的导管消融对消融者来说仍是一项挑战，因为该疾病现在已超出静脉范围，无法仅通过肺静脉隔离来解决。在本文中，我们描述了将靶向碎裂心房电图（CFAE）作为一种指导心房基质改良的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/2bd01a9032a7/CCR-8-347_F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/22208d902518/CCR-8-347_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/72e9c2f3a96b/CCR-8-347_F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/aa4ec08a2e17/CCR-8-347_F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/2bd01a9032a7/CCR-8-347_F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/22208d902518/CCR-8-347_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/72e9c2f3a96b/CCR-8-347_F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/aa4ec08a2e17/CCR-8-347_F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea55/3492817/2bd01a9032a7/CCR-8-347_F4.jpg

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Hot potatoes in AF.

本文引用的文献

1
Substrate modification by pulmonary vein isolation and left atrial linear ablation in patients with persistent atrial fibrillation: its impact on complex-fractionated atrial electrograms.肺静脉隔离和左心房线性消融术对持续性心房颤动患者的基质修饰：对复杂碎裂心房电图的影响。
J Cardiovasc Electrophysiol. 2012 Sep;23(9):962-70. doi: 10.1111/j.1540-8167.2012.02322.x. Epub 2012 Apr 9.
2
Mapping of complex fractionated atrial electrograms as target sites for AF ablation.将复杂碎裂心房电图标测作为房颤消融的靶点
Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:5539-42. doi: 10.1109/IEMBS.2011.6091413.
3
Functional nature of electrogram fractionation demonstrated by left atrial high-density mapping.
房颤中的棘手问题。
Curr Cardiol Rev. 2012 Nov;8(4):251-2. doi: 10.2174/157340312803760776.
左房高密度标测显示心内电图碎裂的功能性本质。
Circ Arrhythm Electrophysiol. 2012 Feb;5(1):32-42. doi: 10.1161/CIRCEP.111.964197. Epub 2012 Jan 3.
4
The role of fibroblasts in complex fractionated electrograms during persistent/permanent atrial fibrillation: implications for electrogram-based catheter ablation.成纤维细胞在持续性/永久性心房颤动时复杂碎裂电图中的作用：对基于电图的导管消融的影响。
Circ Res. 2012 Jan 20;110(2):275-84. doi: 10.1161/CIRCRESAHA.111.255026. Epub 2011 Dec 15.
5
Catheter ablation of right atrial ganglionated plexi in patients with vagal paroxysmal atrial fibrillation.导管消融右心房神经丛在迷走神经性阵发性心房颤动患者中的应用。
Circ Arrhythm Electrophysiol. 2012 Feb;5(1):22-31. doi: 10.1161/CIRCEP.111.964262. Epub 2011 Dec 6.
6
The Modified Ablation Guided by Ibutilide Use in Chronic Atrial Fibrillation (MAGIC-AF) Study: clinical background and study design.伊布利特指导下改良的房颤消融研究（MAGIC-AF）：临床背景和研究设计。
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Differences in repeating patterns of complex fractionated left atrial electrograms in longstanding persistent atrial fibrillation as compared with paroxysmal atrial fibrillation.与阵发性心房颤动相比，持续性心房颤动中复杂碎裂左房电图重复模式的差异。
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10
Pulmonary vein isolation with complex fractionated atrial electrogram ablation for paroxysmal and nonparoxysmal atrial fibrillation: A meta-analysis.采用复杂碎裂心房电图消融术进行阵发性和非阵发性心房颤动的肺静脉隔离：一项荟萃分析。
Heart Rhythm. 2011 Jul;8(7):994-1000. doi: 10.1016/j.hrthm.2011.02.033. Epub 2011 Mar 10.