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超声心动图在肺动脉高压中的应用。

Echocardiography in pulmonary arterial hypertension.

机构信息

Hospital of University of Pennsylvania, Department of Medicine, Cardiovascular Medicine Division, Philadelphia, Pennsylvania, USA.

出版信息

Am J Cardiol. 2012 Sep 15;110(6 Suppl):16S-24S. doi: 10.1016/j.amjcard.2012.06.012.

Abstract

In the context of pulmonary arterial hypertension (PAH), echocardiographic assessment of right ventricular (RV) function is key to determining disease severity and prognosis. Using Doppler echocardiography (ECHO) there are numerous ways that RV function can be measured, either directly or indirectly, to capture the triad of changes in RV geometry, right-to-left interaction, and RV systolic dysfunction in response to high pulmonary vascular resistance states, such as PAH. To fully evaluate and characterize the nature and extent of the impact of PAH on the RV in an individual patient, it is critical to assess a combination of these direct and indirect measures of RV function. In order to predict changes in status and have prognostic significance, the variables used must be easy to measure, reproducible, and clinically relevant. This review assesses the relative value of different ECHO parameters and looks at what the future holds for ECHO imaging of the right heart in PAH.

摘要

在肺动脉高压(PAH)的背景下,超声心动图评估右心室(RV)功能对于确定疾病严重程度和预后至关重要。使用多普勒超声心动图(ECHO),可以通过直接或间接的方式测量 RV 功能的多个方面,以捕捉 RV 几何形状、右向左相互作用和 RV 收缩功能的三重变化,以应对高肺血管阻力状态,如 PAH。为了全面评估和描述 PAH 对个体患者 RV 的影响的性质和程度,评估 RV 功能的这些直接和间接测量的组合非常关键。为了预测病情变化并具有预后意义,所用变量必须易于测量、可重复且具有临床相关性。本综述评估了不同 ECHO 参数的相对价值,并探讨了 PAH 右心 ECHO 成像的未来发展方向。

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