Division of Vaccine Preventable Disease Control and National Immunization Program, Korea Centers for Disease Control and Prevention, Osong, Korea.
Int J Infect Dis. 2012 Dec;16(12):e850-4. doi: 10.1016/j.ijid.2012.07.012. Epub 2012 Aug 22.
Although there has been substantial progress in controlling pertussis in South Korea, the reported number of pertussis case-patients has gradually been increasing during the last decade. To address this, we summarized the surveillance data on pertussis collected during the period 1955-2011. Detailed epidemiologic and clinical data were determined, primarily using data from recent years.
We analyzed data from the national surveillance system to describe the occurrence of pertussis. The annual numbers of reported pertussis case-patients were identified for the period 1955-2000. For 2001-2009, information including limited demographic characteristics and the date of onset of symptoms were identified. For 2010-2011, detailed epidemiologic and clinical information of reported pertussis case-patients were collected.
During 1955-2011, the secular trend was characterized by a gradual decrease in the reported number of cases from 1955 to the late 1990s, then a recent increase starting in the early 2000s. In 2009, a large number of reported cases occurred in infants <1 year of age. In 2011, an increase in reported cases among adolescents and adults aged ≥15 years was observed. During 2010-2011, 29.8% of reported cases were not immunized and 11.3% had not been immunized in a timely manner. Of adolescents and adults aged ≥15 years, 91.7% did not have a record of immunization.
During 2010-2011, a shift in age group was observed in pertussis case-patients: 33.8% were young infants <3 months of age and 29.0% were adolescents and adults ≥15 years of age. Considering that infants without timely vaccination may be vulnerable to an increased risk of pertussis infection, steps to provide timely vaccination to infants, to provide Tdap vaccination to adolescents and adults, and to enhance surveillance to capture adult pertussis cases should be taken in South Korea.
尽管韩国在控制百日咳方面取得了重大进展，但在过去十年中，报告的百日咳病例数逐渐增加。为了解决这个问题，我们总结了 1955 年至 2011 年期间收集的百日咳监测数据。主要使用近年来的数据确定了详细的流行病学和临床数据。
我们分析了国家监测系统中的数据，以描述百日咳的发生情况。确定了 1955 年至 2000 年期间报告的百日咳病例数。对于 2001 年至 2009 年，确定了包括有限的人口统计学特征和症状发作日期在内的信息。对于 2010 年至 2011 年，收集了报告的百日咳病例的详细流行病学和临床信息。
在 1955 年至 2011 年期间，报告病例的季节性趋势表现为从 1955 年到 20 世纪 90 年代末的逐渐减少，然后从 21 世纪初开始最近有所增加。2009 年，大量报告病例发生在<1 岁的婴儿中。2011 年，观察到青少年和≥15 岁的成年人报告病例数增加。在 2010 年至 2011 年期间，29.8%的报告病例未接种疫苗，11.3%未及时接种疫苗。在青少年和≥15 岁的成年人中，91.7%没有接种记录。
在 2010 年至 2011 年期间，百日咳病例患者的年龄组发生了转变：33.8%是<3 个月的婴儿，29.0%是青少年和≥15 岁的成年人。考虑到未及时接种疫苗的婴儿可能面临更高的百日咳感染风险，韩国应采取措施及时为婴儿接种疫苗，为青少年和成年人接种 Tdap 疫苗，并加强监测以捕捉成人百日咳病例。
