Department of Neuropsychiatry, The Barberry National Centre for Mental Health, BSMHFT, Birmingham, UK.
Compr Psychiatry. 2013 Feb;54(2):105-10. doi: 10.1016/j.comppsych.2012.07.004. Epub 2012 Aug 24.
Tourette syndrome (TS) can increase the likelihood of social and emotional difficulties which may shape an individual's personality and self-perception. We investigated personality and affect in patients with TS.
Twenty-five adults with TS (2 with co-morbid obsessive compulsive disorder, 4 with co-morbid attention-deficit hyperactivity disorder and 4 with both co-morbidities), who were not clinically depressed, and 25 matched controls participated in the study. They completed the Ten-Item Personality Index, the Positive and Negative Affect Scale and the Beck Depression Inventory.
Adults with TS exhibited no differences from controls in reported emotional experience or depressive symptoms but did differ for four of the five assessed personality dimensions; extraversion, conscientiousness, openness and emotional stability. Individuals with pure TS (who had no co-morbid conditions) exhibited reduced extraversion and emotional stability compared to controls. Personality scores were not related to tic severity, yet lower emotional stability scores were associated with higher ratings of negative affect.
This study is limited by a restricted sample in terms of size and source. However, our findings indicate that in the absence of depression and common co-morbidities, people with TS differ from controls in indices of personality, which are linked to negative affectivity.
妥瑞氏症（TS）可能增加社交和情绪困难的可能性，从而影响个人的个性和自我认知。我们研究了 TS 患者的个性和情绪。
25 名成年 TS 患者（2 名合并强迫症，4 名合并注意缺陷多动障碍，4 名同时合并两种疾病），无临床抑郁，与 25 名匹配的对照组参与者。他们完成了十项人格指标、正性和负性情绪量表以及贝克抑郁量表。
TS 组与对照组在情绪体验或抑郁症状方面无差异，但在五个评估人格维度中的四个方面存在差异；外向性、尽责性、开放性和情绪稳定性。单纯 TS 患者（无合并症）与对照组相比，外向性和情绪稳定性降低。人格评分与抽搐严重程度无关，但情绪稳定性评分较低与更高的负性情绪评分相关。
本研究受到样本大小和来源的限制。然而，我们的发现表明，在没有抑郁和常见合并症的情况下，TS 患者与对照组在人格指数上存在差异，这与负性情绪有关。
