*Department of Ophthalmology and Visual Sciences, University of Illinois-Chicago, Chicago, IL †Cornea Research Foundation of America ‡Price Vision Group, Indianapolis, IN §Wilmer Eye Institute, Johns Hopkins University Baltimore, MD ∥King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
J Glaucoma. 2014 Mar;23(3):142-4. doi: 10.1097/IJG.0b013e31826a96cd.
To study the relationship of ocular pulse amplitude (OPA) and intraocular pressure (IOP) in eyes that have undergone successful Descemet stripping endothelial keratoplasty (DSEK).
Fifty eyes of 38 patients with successful DSEK at a single tertiary referral center were followed up for at least 3 months. At the time of the study all patients were carefully examined to rule out any clinically detectable corneal edema. IOP was measured by Goldmann applanation tonometry (GAT), pneumotonometry (PT), and dynamic contour tonometry (DCT). IOP, OPA, and quality measurements were recorded. Central corneal thickness (CCT) was measured by ultrasonic pachymetry.
Mean IOP was 15.9±4.9 mm Hg by GAT, 20.3±4.6 mm Hg by PT, and 19.8±4.4 mm Hg by DCT. Mean OPA was 2.53±1.24 mm Hg. OPA was correlated with GAT (r=0.357, P=0.011) and PT (r=0.316, P=0.026). The correlation of OPA and DCT approached significance (r=0.270, P=0.058). Mean CCT was 701±65 µm (range, 529 to 928 µm). OPA was not associated with CCT (r=0.238, P=0.096).
In eyes with DSEK, our results showed that OPA was similar to that reported in normal eyes. Comparable with results in normal eyes, OPA was not associated with CCT but was associated with increasing IOP in DSEK eyes.
研究成功接受 Descemet 撕囊内皮角膜移植术（DSEK）后的眼的眼脉冲振幅（OPA）和眼内压（IOP）之间的关系。
在一家三级转诊中心成功接受 DSEK 的 38 例患者的 50 只眼进行了至少 3 个月的随访。在研究时，所有患者均经过仔细检查，以排除任何临床上可检测到的角膜水肿。通过 Goldmann 压平眼压计（GAT）、气动眼压计（PT）和动态轮廓眼压计（DCT）测量眼压。记录眼压、OPA 和质量测量值。使用超声角膜测厚仪测量中央角膜厚度（CCT）。
GAT 测量的平均眼压为 15.9±4.9mmHg，PT 测量的平均眼压为 20.3±4.6mmHg，DCT 测量的平均眼压为 19.8±4.4mmHg。平均 OPA 为 2.53±1.24mmHg。OPA 与 GAT（r=0.357，P=0.011）和 PT（r=0.316，P=0.026）相关。OPA 与 DCT 的相关性接近显著（r=0.270，P=0.058）。平均 CCT 为 701±65µm（范围 529 至 928µm）。OPA 与 CCT 无关（r=0.238，P=0.096）。
在 DSEK 眼中，我们的结果表明 OPA 与正常眼报道的结果相似。与正常眼的结果一样，OPA 与 CCT 无关，但与 DSEK 眼的眼压升高有关。
