College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, China.
J Virol. 2012 Sep;86(18):10238. doi: 10.1128/JVI.01601-12.
We report here the complete genomic sequence of an avian-origin H3N2 canine influenza A virus containing multiple mutations in farmed dogs in southern China. Phylogenetic analyses of the sequences of all eight viral RNA segments demonstrated that these are wholly avian influenza viruses of the Asia lineage. To our knowledge, this is the first report of interspecies transmission of an avian H3N2 influenza virus to domestic farm dogs under natural conditions in Southern China. The amino acid information provided herein suggests that continued study is required to determine if this virus could be established in the farm dog population and pose potential threats to public health.
我们在此报告了一株源自禽类的 H3N2 犬流感 A 病毒的完整基因组序列，该病毒在中国南方的养殖犬群中存在多种突变。对所有 8 个病毒 RNA 片段序列的系统进化分析表明，这些病毒均为亚洲谱系的禽流感病毒。据我们所知，这是首次在自然条件下报告在中国南方发生的一种禽类 H3N2 流感病毒向家养犬种的种间传播。本文提供的氨基酸信息提示，需要进一步研究来确定该病毒是否能在养殖犬群中建立并对公共卫生构成潜在威胁。
