一名14岁女性卵巢囊肿增大，伴有持续性腹水、严重甲状腺功能减退及血清CA-125水平升高。
Ovarian Cyst Enlargement in a 14 Year Old Female with Persistent Ascities, Severe Hypothyroidism and Elevated Serum CA-125 Level.
作者信息
Motamed F, Eftekhari K, Kiani M A, Rabbani A
机构信息
Department of Gastroenterology, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Iran Red Crescent Med J. 2012 Jun;14(6):379-81. Epub 2012 Jun 30.
Abstract
A 14 year old female complained of abdominal pain and distention with vomiting. The physical exam showed thyroid enlargement and ascites. The imaging evaluation demonstrated a large ovarian cyst. Laboratory tests depicted hypothyroidism and marked elevation of Carbohydrate antigen 125 (CA-125) levels. As the bone age was 10 years, more retarded than the chronological age, Van Wyk and Grumbach syndrome was suspected. Treatment with thyroid hormone was initiated and the condition improved dramatically with disappearance of symptoms and signs 5 weeks later.
摘要
一名14岁女性主诉腹痛、腹胀伴呕吐。体格检查发现甲状腺肿大及腹水。影像学评估显示有一个巨大的卵巢囊肿。实验室检查显示甲状腺功能减退以及糖类抗原125（CA - 125）水平显著升高。由于骨龄为10岁，比实际年龄滞后，怀疑为范·怀克和格伦巴赫综合征。开始用甲状腺激素治疗，5周后症状和体征消失，病情显著改善。
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