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肺外黏液样软骨肉瘤:无症状肺肿块伴严重贫血。

Extraskeletal myxoid chondrosarcoma in the lung: asymptomatic lung mass with severe anemia.

机构信息

Department of General thoracic surgery, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, PR China.

出版信息

Diagn Pathol. 2012 Aug 28;7:112. doi: 10.1186/1746-1596-7-112.

Abstract

Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft-tissue sarcoma, which primarily occurs deep in the extremities, especially in skeletal muscle, or tendon. EMC of the pleura has been described, however, no case of primary EMC arising from lung has been previously reported. We describe herein, a 51-year-old Asian female initially manifested with signs of severe anemia who presented with a lung mass unrelated to pleura that was morphologically typical EMC, with strong immunoreactivity for vimentin and NSE. Two weeks after resection, the anemia was cured. The patient continued with follow-up, without sign of abnormality 32 months after operation. Virtual slides: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2882199847396682.

摘要

骨外黏液样软骨肉瘤(EMC)是一种罕见的软组织肉瘤,主要发生在四肢深部,尤其是在骨骼肌或肌腱中。胸膜的 EMC 已有描述,但以前没有报告过原发性 EMC 源自肺部的病例。我们在此描述了一位 51 岁的亚洲女性,最初表现为严重贫血的症状,她出现了与胸膜无关的肺部肿块,形态学上为典型的 EMC,对波形蛋白和 NSE 具有强烈的免疫反应性。切除两周后,贫血得到治愈。患者继续随访,术后 32 个月无异常迹象。虚拟幻灯片:本文的虚拟幻灯片可在此处找到:http://www.diagnosticpathology.diagnomx.eu/vs/2882199847396682。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d25/3487864/b95c319013ae/1746-1596-7-112-1.jpg

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