黄芪属（NAB.）野兔皂甙

Saponins from Astragalus hareftae (NAB.) SIRJ.

机构信息

Department of Chemistry, Faculty of Science, Ege University, 35100 Bornova, İzmir, Turkey.

出版信息

Phytochemistry. 2012 Dec;84:147-53. doi: 10.1016/j.phytochem.2012.07.015. Epub 2012 Aug 25.

DOI:10.1016/j.phytochem.2012.07.015

Abstract

Four cycloartane- (hareftosides A-D) and oleanane-type triterpenoids (hareftoside E) were isolated from Astragalus hareftae along with fifteen known compounds. Structures of the compounds were established as 3,6-di-O-β-D-xylopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane, 3,6,24-tri-O-β-D-xylopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane, 3-O-β-D-xylopyranosyl-3β,6α,16β,25-tetrahydroxy-20(R),25(S)-epoxycycloartane, 16-O-β-D-glucopyranosyl-3β,6α,16β,25-tetrahydroxy-20(R),24(S)-epoxycycloartane, 3-O-[β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-O-β-D-glucuronopyranosyl]-soyasapogenol B by the extensive use of 1D- and 2D-NMR experiments along with ESI-MS and HR-MS analyses.

摘要

从红花黄芪中分离得到了四种环阿屯烷-（哈夫托苷 A-D）和齐墩果烷型三萜（哈夫托苷 E），以及十五种已知化合物。通过广泛使用 1D 和 2D-NMR 实验以及 ESI-MS 和 HR-MS 分析，确定了这些化合物的结构为 3,6-二-O-β-D-吡喃木糖基-3β,6α,16β,24(S),25-五羟基环阿屯烷、3,6,24-三-O-β-D-吡喃木糖基-3β,6α,16β,24(S),25-五羟基环阿屯烷、3-O-β-D-吡喃木糖基-3β,6α,16β,25-四羟基-20(R),25(S)-环氧环阿屯烷、16-O-β-D-吡喃葡萄糖基-3β,6α,16β,25-四羟基-20(R),24(S)-环氧环阿屯烷、3-O-[β-D-吡喃木糖基-(1→2)-O-β-D-吡喃葡萄糖基-(1→2)-O-β-D-吡喃葡萄糖醛酸基]-大豆皂醇 B。