Departamento de Química Orgánica, Facultad de Química, Universidad de Vigo, 36200 Vigo, Spain.
Bioorg Med Chem Lett. 2012 Oct 1;22(19):6276-9. doi: 10.1016/j.bmcl.2012.07.095. Epub 2012 Aug 7.
A new vitamin D(2) analogue was synthesized using the Julia-Kocienski olefination. It has antiproliferative effects on cell lines from squamous cell carcinomas of colon and head and neck, but is also as hypercalcaemic as calcitriol in vivo.
一种新的维生素 D(2)类似物是使用 Julia-Kocienski 烯烃合成法合成的。它对结肠和头颈部鳞状细胞癌的细胞系具有抗增殖作用，但在体内也像骨化三醇一样引起高钙血症。
