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玻璃体切除术治疗特发性全层黄斑裂孔后的长期随访:视力与黄斑并发症

Long-term follow-up after vitrectomy to treat idiopathic full-thickness macular holes: visual acuity and macular complications.

作者信息

Sakaguchi Hirokazu, Ohji Masahito, Oshima Yusuke, Ikuno Yasushi, Gomi Fumi, Maeda Naoyuki, Kamei Motohiro, Kusaka Shunji, Nishida Kohji

机构信息

Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita.

出版信息

Clin Ophthalmol. 2012;6:1281-6. doi: 10.2147/OPTH.S34629. Epub 2012 Aug 9.

Abstract

BACKGROUND

To assess time-course changes in best-corrected visual acuity (BCVA) up to 5 years after vitrectomy to treat idiopathic full-thickness macular holes (MHs) and identify the relationship of the changes to postoperative complications.

METHODS

Twenty-three consecutive patients with an idiopathic MH underwent vitrectomy without adjuvant treatment. BCVA and complications were assessed postoperatively.

RESULTS

Twenty-two of 23 (95.7%) MHs closed after the first surgery, with a final anatomic success rate of 100%. The time course of the BCVA was analyzed in 20 cases in which data were obtained for over 5 years. The BCVA improved by 0.43 logarithm of the minimum angle of resolution (logMAR) unit 6 months postoperatively (P < 0.001) and continuously improved by 0.05, 0.06, and 0.07 logMAR units between 6 months and 1 year, 1 year and 3 years (by 0.11 logMAR unit between 6 months and 3 years; P = 0.049), and 3 years and 5 years (P = 0.018) postoperatively, respectively. Macular complications developed in seven (35%) of the 20 cases; the mean BCVA at 5 years in these cases was significantly (P < 0.001) worse than in cases without complications.

CONCLUSION

The BCVA might improve gradually for 5 years after vitrectomy to treat MHs. However, the macular complications that can develop postoperatively could limit that possibility.

摘要

背景

评估玻璃体切割术治疗特发性全层黄斑裂孔(MHs)后长达5年的最佳矫正视力(BCVA)的时间进程变化,并确定这些变化与术后并发症的关系。

方法

23例连续的特发性MH患者接受了无辅助治疗的玻璃体切割术。术后评估BCVA和并发症。

结果

23例中的22例(95.7%)MHs在首次手术后闭合,最终解剖成功率为100%。对20例获得超过5年数据的病例分析了BCVA的时间进程。术后6个月BCVA提高了0.43最小分辨角对数(logMAR)单位(P < 0.001),在术后6个月至1年、1年至3年(6个月至3年提高了0.11 logMAR单位;P = 0.049)以及3年至5年(P = 0.018)之间分别持续提高0.05、0.06和0.07 logMAR单位。20例中有7例(35%)发生黄斑并发症;这些病例5年时的平均BCVA显著(P < 0.001)差于无并发症的病例。

结论

玻璃体切割术治疗MHs后,BCVA可能会在5年内逐渐改善。然而,术后可能发生的黄斑并发症可能会限制这种可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a474/3422155/3ea7188a6928/opth-6-1281f1.jpg

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