Department of Periodontology and Oral Medicine, University of Niš, Niš, Serbia.
Diabetes Technol Ther. 2012 Sep;14(9):799-803. doi: 10.1089/dia.2012.0027.
Diabetes mellitus (DM) increases the risk of periodontitis, and severe periodontitis often coexists with severe DM. The proposed dual pathway of tissue destruction suggests that control of chronic periodontal infection and gingival inflammation is essential for achieving long-term control of DM. The purpose this study is to evaluate the effects of low-level laser therapy (LLLT) by exfoliative cytology in patients with DM and gingival inflammation.
Three hundred patients were divided in three equal groups: Group 1 consisted of patients with periodontitis and type 1 DM, Group 2 of patients with periodontitis and type 2 DM, and Group 3 of patients with periodontitis (control group). After oral examination, smears were taken from gingival tissue, and afterward all of the patients received oral hygiene instructions, removal of dental plaque, and full-mouth scaling and root planing. A split-mouth design was applied; on the right side of jaws GaAlAs LLLT (670 nm, 5 mW, 14 min/day) (model Mils 94; Optica Laser, Sofia, Bulgaria) was applied for five consecutive days. After the therapy was completed, smears from both sides of jaws were taken. The morphometric analysis was done using the National Institutes of Health Image software program and a model NU2 microscope (Carl Zeiss, Jena, Germany).
Investigated parameters were significantly lower after therapy compared with values before therapy. After therapy on the side subjected to LLLT, there was no significantly difference between patients with DM and the control group.
It can be concluded that LLLT as an adjunct in periodontal therapy reduces gingival inflammation in patients with DM and periodontitis.
糖尿病(DM)会增加牙周炎的风险,而严重的牙周炎常与严重的 DM 并存。组织破坏的双重途径表明,控制慢性牙周感染和牙龈炎症对于长期控制 DM 至关重要。本研究旨在评估低水平激光疗法(LLLT)对糖尿病伴牙龈炎症患者的疗效。
将 300 名患者分为三组:组 1 为 1 型糖尿病伴牙周炎患者,组 2 为 2 型糖尿病伴牙周炎患者,组 3 为牙周炎患者(对照组)。口腔检查后,从牙龈组织中取出涂片,然后所有患者均接受口腔卫生指导、牙菌斑清除、全口洁治和根面平整。采用分口设计,右侧下颌骨应用 GaAlAs LLLT(670nm,5mW,14min/d)(Optica Laser,Sofia,保加利亚)连续 5 天。治疗完成后,从双侧下颌骨取出涂片。使用国家卫生研究院图像软件程序和 NU2 显微镜(Carl Zeiss,耶拿,德国)进行形态计量分析。
与治疗前相比,治疗后各参数均显著降低。在接受 LLLT 的一侧治疗后,DM 患者与对照组之间无显著差异。
可以得出结论,LLLT 作为牙周治疗的辅助手段可减轻糖尿病伴牙周炎患者的牙龈炎症。