Ghajarzadeh Mahsa, Ghiasi Maryam, Kheirkhah Shahrbanoo
Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Iran.
Acta Med Iran. 2012;50(7):511-5.
The goal of this study was to compare depression and quality of life in three auto immune diseases: psoriasis, vitiligo, and alopecia areata. From January 2009 until January 2010, 300 patients (100 with alopecia areata, 100 with psoriasis and 100 with vitiligo) who were randomly selected (by simple random selection) from outpatient clinic of Razi Hospital (Center of Skin Diseases of Tehran University of Medical Sciences) were asked to answer to Beck Depression Inventory (BDI), SF-36 and Dermatology Life Quality Index (DLQI) questionnaires. DLQI scores were significantly higher in psoriasis cases than others (12.8 ± 6.1, P<0.0001) and SF-36 score were significantly lower (59.8 ± 19.5, P=0.007), both indicating poor quality of life. Significant correlation was found between DLQI and BDI in all disease groups (r=0.44, P<0.001). BDI scores were the highest in psoriasis group but this difference was not significant (P=0.2). Based on these results, dermatologists should consider psychological aspects of autoimmune skin diseases.
本研究的目的是比较三种自身免疫性疾病（银屑病、白癜风和斑秃）患者的抑郁情况和生活质量。2009年1月至2010年1月期间，从拉齐医院（德黑兰医科大学皮肤病中心）门诊随机选取300例患者（100例斑秃患者、100例银屑病患者和100例白癜风患者），要求他们回答贝克抑郁量表（BDI）、SF-36健康调查简表和皮肤病生活质量指数（DLQI）问卷。银屑病患者的DLQI评分显著高于其他患者（12.8±6.1，P<0.0001），而SF-36评分显著低于其他患者（59.8±19.5，P=0.007），这两者均表明生活质量较差。所有疾病组的DLQI与BDI之间均存在显著相关性（r=0.44，P<0.001）。银屑病组的BDI评分最高，但差异不显著（P=0.2）。基于这些结果，皮肤科医生应考虑自身免疫性皮肤病的心理方面。
