Department of Dermatology and Venereology, University of Tartu, Tartu, Estonia.
Acta Derm Venereol. 2013 Jul 6;93(4):446-50. doi: 10.2340/00015555-1520.
The impact of vitiligo on quality of life is controversial. The aim of this study was to observe the impairment of quality of life and emotional state in adults with vitiligo compared with subjects with psoriasis and unaffected controls. The study group comprised 54 subjects with vitiligo, 57 with psoriasis and 57 unaffected controls. All subjects were examined and interviewed using the Dermatology Life Quality Index (DLQI) and Emotional State questionnaires. The total mean DLQI score in vitiligo was 4.7, compared with 0.6 in healthy controls (p<0.001) and 13.1 in psoriasis (p<0.001). In vitiligo, females experienced a greater impact on feelings and men experienced a greater impact on relationships. Lower quality of life in vitiligo was associated with active stage of the disease, extension of pigment loss, depigmentation on the hands, and earlier onset of disease. The results demonstrate that vitiligo has less impact on quality of life than psoriasis.
白癜风对生活质量的影响存在争议。本研究旨在观察与银屑病患者和无皮损对照者相比，成人白癜风患者生活质量和情绪状态的损害。研究组包括 54 例白癜风患者、57 例银屑病患者和 57 例无皮损对照者。所有患者均采用皮肤病生活质量指数（DLQI）和情绪状态问卷进行检查和访谈。白癜风患者的 DLQI 总平均分为 4.7，而健康对照组为 0.6（p<0.001），银屑病患者为 13.1（p<0.001）。在白癜风患者中，女性在情感方面受到的影响更大，而男性在人际关系方面受到的影响更大。白癜风患者生活质量较低与疾病的活动期、色素脱失的扩展、手部的色素脱失以及疾病的早期发病有关。研究结果表明，白癜风对生活质量的影响小于银屑病。
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