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上丘参与杏仁核点燃癫痫控制的证据。

Evidence that superior colliculi are involved in the control of amygdala-kindled seizures.

作者信息

N'Gouemo P, Rondouin G

机构信息

Laboratoire de Médecine Expérimentale, INSERM U249, CNRS UPR41, Institut de Biologie, Montpellier, France.

出版信息

Neurosci Lett. 1990 Nov 27;120(1):38-41. doi: 10.1016/0304-3940(90)90162-3.

DOI:10.1016/0304-3940(90)90162-3
PMID:2293088
Abstract

The effects of bilateral high radiofrequency lesions of superior colliculus (SC) were studied on amygdala kindling. The results demonstrate that a selective destruction of the SC only slightly facilitated the development of kindling. However, the most remarkable effect was the increase of afterdischarge and motor seizure duration observed when SC-lesioned animals reached the generalized seizures. These data confirm that the superior colliculi participate in controlling the generalization of kindled seizures.

摘要

研究了双侧上丘(SC)高频损伤对杏仁核点燃的影响。结果表明,选择性破坏上丘仅略微促进了点燃的发展。然而,最显著的影响是在双侧上丘损伤的动物出现全身性惊厥时,观察到其放电后时间和运动性惊厥持续时间增加。这些数据证实上丘参与控制点燃性惊厥的泛化。

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