Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, Fujian, PR China.
Org Lett. 2012 Sep 21;14(18):4958-61. doi: 10.1021/ol302323a. Epub 2012 Aug 29.
A novel Au-catalyzed tandem cycloisomerization/oxidation of homopropargyl alcohols was developed. Various γ-lactones can be accessed readily by utilizing this strategy. Notably, the mechanism of this reaction is distinctively different from the related Ru-catalyzed reactions where the ruthenium vinylidene intermediate was proposed.
发展了一种新型的 Au 催化的偕丙醇的串联环化/氧化反应。通过利用该策略，可以很容易地获得各种 γ-内酯。值得注意的是，该反应的机理明显不同于相关的 Ru 催化反应，其中提出了钌烯丙基中间体。
