Department of Neurosurgery, UMC Ljubljana, Slovenia.
Radiol Oncol. 2011 Sep;45(3):159-65. doi: 10.2478/v10019-011-0018-3. Epub 2011 Jul 20.
Malignant gliomas account for a high proportion of brain tumours. With new advances in neurooncology, the recurrence-free survival of patients with malignant gliomas has been substantially prolonged. It, however, remains dependent on the thoroughness of the surgical resection. The maximal tumour resection without additional postoperative deficit is the goal of surgery on patients with malignant gliomas. In order to minimize postoperative deficit, several pre- and intraoperative techniques have been developed.
Several techniques used in malignant glioma surgery have been developed, including microsurgery, neuroendoscopy, stereotactic biopsy and brachytherapy. Imaging and functional techniques allowing for safer tumour resection have a special value. Imaging techniques allow for better preoperative visualization and choice of the approach, while functional techniques help us locate eloquent regions of the brain.
恶性脑胶质瘤占脑肿瘤的很大一部分。随着神经肿瘤学的新进展,恶性脑胶质瘤患者的无复发生存期已大大延长。然而,这仍然取决于手术切除的彻底性。对于恶性脑胶质瘤患者,最大程度地切除肿瘤而不增加术后缺陷是手术的目标。为了最大限度地减少术后缺陷,已经开发了几种术前和术中技术。
已经开发了几种用于恶性脑胶质瘤手术的技术,包括显微镜手术、神经内镜、立体定向活检和近距离放疗。允许更安全地切除肿瘤的成像和功能技术具有特殊价值。成像技术可更好地进行术前可视化和选择入路,而功能技术可帮助我们定位大脑的功能区。