• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

恶性胶质瘤外科治疗的新进展。

New developments in surgery of malignant gliomas.

机构信息

Department of Neurosurgery, UMC Ljubljana, Slovenia.

出版信息

Radiol Oncol. 2011 Sep;45(3):159-65. doi: 10.2478/v10019-011-0018-3. Epub 2011 Jul 20.

DOI:10.2478/v10019-011-0018-3
PMID:22933950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3423736/
Abstract

BACKGROUND

Malignant gliomas account for a high proportion of brain tumours. With new advances in neurooncology, the recurrence-free survival of patients with malignant gliomas has been substantially prolonged. It, however, remains dependent on the thoroughness of the surgical resection. The maximal tumour resection without additional postoperative deficit is the goal of surgery on patients with malignant gliomas. In order to minimize postoperative deficit, several pre- and intraoperative techniques have been developed.

CONCLUSIONS

Several techniques used in malignant glioma surgery have been developed, including microsurgery, neuroendoscopy, stereotactic biopsy and brachytherapy. Imaging and functional techniques allowing for safer tumour resection have a special value. Imaging techniques allow for better preoperative visualization and choice of the approach, while functional techniques help us locate eloquent regions of the brain.

摘要

背景

恶性脑胶质瘤占脑肿瘤的很大一部分。随着神经肿瘤学的新进展,恶性脑胶质瘤患者的无复发生存期已大大延长。然而,这仍然取决于手术切除的彻底性。对于恶性脑胶质瘤患者,最大程度地切除肿瘤而不增加术后缺陷是手术的目标。为了最大限度地减少术后缺陷,已经开发了几种术前和术中技术。

结论

已经开发了几种用于恶性脑胶质瘤手术的技术,包括显微镜手术、神经内镜、立体定向活检和近距离放疗。允许更安全地切除肿瘤的成像和功能技术具有特殊价值。成像技术可更好地进行术前可视化和选择入路,而功能技术可帮助我们定位大脑的功能区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/3c1a662a9cb5/rado-45-03-159f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/8f04c1cae54c/rado-45-03-159f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/1b07f9218115/rado-45-03-159f2A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/415fe56c5ba5/rado-45-03-159f2B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/e21816ec4224/rado-45-03-159f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/d6f910595e9f/rado-45-03-159f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/4fa0f1185b76/rado-45-03-159f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/fa1a5b3a14a4/rado-45-03-159f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/ec376203445d/rado-45-03-159f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/3c1a662a9cb5/rado-45-03-159f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/8f04c1cae54c/rado-45-03-159f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/1b07f9218115/rado-45-03-159f2A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/415fe56c5ba5/rado-45-03-159f2B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/e21816ec4224/rado-45-03-159f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/d6f910595e9f/rado-45-03-159f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/4fa0f1185b76/rado-45-03-159f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/fa1a5b3a14a4/rado-45-03-159f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/ec376203445d/rado-45-03-159f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d3/3423736/3c1a662a9cb5/rado-45-03-159f8.jpg

相似文献

1
New developments in surgery of malignant gliomas.恶性胶质瘤外科治疗的新进展。
Radiol Oncol. 2011 Sep;45(3):159-65. doi: 10.2478/v10019-011-0018-3. Epub 2011 Jul 20.
2
Surgery of malignant motor-eloquent gliomas guided by sodium-fluorescein and navigated transcranial magnetic stimulation: a novel technique to increase the maximal safe resection.荧光素钠引导及导航经颅磁刺激辅助下的恶性运动功能区胶质瘤手术:一种提高最大安全切除范围的新技术
J Neurosurg Sci. 2019 Dec;63(6):670-678. doi: 10.23736/S0390-5616.19.04710-6. Epub 2019 May 6.
3
Introduction of a standardized multimodality image protocol for navigation-guided surgery of suspected low-grade gliomas.用于疑似低级别胶质瘤导航引导手术的标准化多模态影像方案介绍。
Neurosurg Focus. 2015 Jan;38(1):E4. doi: 10.3171/2014.10.FOCUS14597.
4
Impact of the combination of 5-aminolevulinic acid-induced fluorescence with intraoperative magnetic resonance imaging-guided surgery for glioma.5-氨基酮戊酸诱导荧光与术中磁共振成像引导手术治疗脑胶质瘤的效果。
World Neurosurg. 2011 Jul-Aug;76(1-2):120-7. doi: 10.1016/j.wneu.2011.02.005.
5
Endoscopic management of a low-grade thalamic glioma: a safe alternative to open microsurgery?低级别丘脑胶质瘤的内镜治疗:开颅显微手术的安全替代方案?
Acta Neurochir (Wien). 2017 Jul;159(7):1237-1240. doi: 10.1007/s00701-017-3120-5. Epub 2017 Feb 24.
6
Improving the extent of malignant glioma resection by dual intraoperative visualization approach.通过双重术中可视化方法提高恶性胶质瘤切除术的范围。
PLoS One. 2012;7(9):e44885. doi: 10.1371/journal.pone.0044885. Epub 2012 Sep 26.
7
Setup presentation and clinical outcome analysis of treating highly language-eloquent gliomas via preoperative navigated transcranial magnetic stimulation and tractography.术前导航经颅磁刺激和轨迹描记术治疗高度语言流利性脑胶质瘤的设置演示和临床结果分析。
Neurosurg Focus. 2018 Jun;44(6):E2. doi: 10.3171/2018.3.FOCUS1838.
8
Cortical plasticity catalyzed by prehabilitation enables extensive resection of brain tumors in eloquent areas.术前康复促进皮质可塑性,有助于在功能区广泛切除脑肿瘤。
J Neurosurg. 2017 Apr;126(4):1323-1333. doi: 10.3171/2016.2.JNS152485. Epub 2016 May 20.
9
Surgical resection of high-grade gliomas in eloquent regions guided by blood oxygenation level dependent functional magnetic resonance imaging, diffusion tensor tractography, and intraoperative navigated 3D ultrasound.在血氧水平依赖性功能磁共振成像、弥散张量纤维束成像和术中导航三维超声引导下,对功能区高级别胶质瘤进行手术切除。
Minim Invasive Neurosurg. 2009 Feb;52(1):17-24. doi: 10.1055/s-0028-1104566. Epub 2009 Feb 26.
10
Comparison of intraoperative fluorescence and MRI image guided neuronavigation in malignant brain tumours, a prospective controlled study.术中荧光与 MRI 图像引导神经导航在恶性脑肿瘤中的比较:一项前瞻性对照研究。
Photodiagnosis Photodyn Ther. 2013 Dec;10(4):356-61. doi: 10.1016/j.pdpdt.2013.03.006. Epub 2013 Apr 17.

引用本文的文献

1
IQGAP1‑siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines.IQGAP1小干扰RNA抑制U251和U373胶质瘤细胞系的增殖和转移。
Mol Med Rep. 2017 Apr;15(4):2074-2082. doi: 10.3892/mmr.2017.6257. Epub 2017 Feb 28.
2
Early medical rehabilitation after neurosurgical treatment of malignant brain tumours in Slovenia.斯洛文尼亚恶性脑肿瘤神经外科治疗后的早期医学康复
Radiol Oncol. 2016 Apr 23;50(2):139-44. doi: 10.1515/raon-2015-0004. eCollection 2016 Jun 1.
3
Functionalized nano-graphene oxide particles for targeted fluorescence imaging and photothermy of glioma U251 cells.

本文引用的文献

1
Frequent MGMT (0(6)-methylguanine-DNA methyltransferase) hypermethylation in long-term survivors of glioblastoma: a single institution experience.胶质母细胞瘤长期幸存者中频繁的 MGMT(O(6)-甲基鸟嘌呤-DNA 甲基转移酶)甲基化:单机构经验。
Radiol Oncol. 2010 Jun;44(2):113-20. doi: 10.2478/v10019-010-0023-y. Epub 2010 May 24.
2
Genetic markers in oligodendroglial tumours.少突胶质细胞瘤的遗传标志物。
Radiol Oncol. 2010 Mar;44(1):13-8. doi: 10.2478/v10019-010-0007-y. Epub 2010 Mar 18.
3
Use of 3D visualisation of medical images for planning and intraoperative localisation of superficial brain tumours: our experience.
用于胶质瘤U251细胞靶向荧光成像和光热治疗的功能化纳米氧化石墨烯颗粒
Int J Clin Exp Med. 2015 Feb 15;8(2):1844-52. eCollection 2015.
4
Glioblastoma patients in Slovenia from 1997 to 2008.2008 年以前斯洛文尼亚的神经胶质瘤患者。
Radiol Oncol. 2014 Jan 22;48(1):72-9. doi: 10.2478/raon-2014-0002. eCollection 2014 Mar.
5
Staurosporine induces different cell death forms in cultured rat astrocytes.星孢菌素诱导培养的大鼠星形胶质细胞产生不同的细胞死亡形式。
Radiol Oncol. 2012 Dec;46(4):312-20. doi: 10.2478/v10019-012-0036-9. Epub 2012 Nov 9.
6
Dosimetric characterizations of GZP6 (60)Co high dose rate brachytherapy sources: application of superimposition method.GZP6(60)Co 高剂量率近距离治疗源的剂量学特性:叠加法的应用。
Radiol Oncol. 2012 Jun;46(2):170-8. doi: 10.2478/v10019-012-0005-3. Epub 2012 Jan 2.
医学图像三维可视化在浅表性脑肿瘤手术规划和术中定位中的应用:我们的经验
Br J Neurosurg. 2010 Oct;24(5):555-60. doi: 10.3109/02688697.2010.496876.
4
First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience.卡莫司汀植入物一线治疗恶性脑胶质瘤,随后行同期放化疗:多中心经验。
Neurosurg Rev. 2010 Oct;33(4):441-9. doi: 10.1007/s10143-010-0280-7. Epub 2010 Aug 13.
5
Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma.神经肿瘤学的激动人心新进展:攻克恶性脑胶质瘤的途径。
CA Cancer J Clin. 2010 May-Jun;60(3):166-93. doi: 10.3322/caac.20069.
6
Navigated transcranial magnetic stimulation for preoperative functional diagnostics in brain tumor surgery.导航经颅磁刺激在脑肿瘤手术术前功能诊断中的应用。
Neurosurgery. 2009 Dec;65(6 Suppl):93-8; discussion 98-9. doi: 10.1227/01.NEU.0000348009.22750.59.
7
Surgical management of intracranial gliomas.
Recent Results Cancer Res. 2009;171:105-24. doi: 10.1007/978-3-540-31206-2_6.
8
Localized BCNU chemotherapy and the multimodal management of malignant glioma.局部卡氮芥化疗与恶性胶质瘤的多模式治疗
Curr Med Res Opin. 2009 Jan;25(1):149-60. doi: 10.1185/03007990802611935.
9
Application of neuroendoscopy to intraventricular lesions.神经内镜在脑室内病变中的应用。
Neurosurgery. 2008 Feb;62 Suppl 2:575-97; discussion 597-8. doi: 10.1227/01.neu.0000316262.74843.dd.
10
Glioma extent of resection and its impact on patient outcome.胶质瘤的切除范围及其对患者预后的影响。
Neurosurgery. 2008 Apr;62(4):753-64; discussion 264-6. doi: 10.1227/01.neu.0000318159.21731.cf.