Sugiyama Atsushi, Imasawa Mitsuhiro, Chiba Tatsuya, Iijima Hiroyuki
Department of Ophthalmology, Faculty of Medicine, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi, 409-3898, Japan.
Open Ophthalmol J. 2012;6:73-4. doi: 10.2174/1874364101206010073. Epub 2012 Aug 10.
We retrospectively reviewed the records of 142 eyes of 138 patients with idiopathic full-thickness macular hole. Spontaneous closure of idiopathic full-thickness macular hole was observed in five eyes (3.5%) of four patients before the planned vitrectomy. In the era when surgical treatment was not available for macular hole, the rate of spontaneous closure of idiopathic full-thickness macular hole was reported as 6.2%. Among several case reports on spontaneous closure of idiopathic full-thickness macular hole based on the optical coherence tomography images only one study reported the rate of spontaneous closure as 2.7%. According to the previous reports and our results, small idiopathic full-thickness macular holes may close spontaneously in a few percent of all macular hole cases. The rate of spontaneous closure may be affected by the waiting time before vitrectomy.
我们回顾性分析了138例特发性全层黄斑裂孔患者的142只眼的病历。在计划行玻璃体切除术之前，4例患者的5只眼（3.5%）观察到特发性全层黄斑裂孔自发闭合。在黄斑裂孔尚无手术治疗的时代，特发性全层黄斑裂孔的自发闭合率报告为6.2%。在仅基于光学相干断层扫描图像的特发性全层黄斑裂孔自发闭合的几例病例报告中，只有一项研究报告自发闭合率为2.7%。根据既往报告和我们的结果，在所有黄斑裂孔病例中，少数特发性小全层黄斑裂孔可能会自发闭合。自发闭合率可能受玻璃体切除术前等待时间的影响。
